Hepatitis C virus infection and non-hepatocellular malignancies in the DAA era: A systematic review and meta-analysis.

Author: MasaroneMario, PersicoMarcello

Paper Details 
Original Abstract of the Article :
Direct antiviral agents have greatly improved therapeutic options for chronic hepatitis C. Indeed, former "difficult-to-treat" patients can now be treated and can achieve sustained response. Hepatitis C virus (HCV) is associated with hepatocellular carcinoma and with B-cell non-Hodgkin lymphoma (B-N...See full text at original site
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引用元:
https://doi.org/10.1111/liv.14119

データ提供:米国国立医学図書館(NLM)

Hepatitis C Virus Infection and Non-Hepatocellular Malignancies: A Comprehensive Review

The advent of direct-acting antivirals (DAAs) has significantly changed the landscape of hepatitis C treatment. This research delves into the complex relationship between hepatitis C virus (HCV) infection and the development of non-hepatocellular malignancies. The authors conducted a systematic review and meta-analysis to investigate this association and to evaluate the impact of DAA therapy on the course of these cancers.

Understanding the Association Between HCV and Non-Hepatocellular Cancers

The review reveals that HCV infection is associated with an increased risk of certain non-hepatocellular malignancies, including B-cell non-Hodgkin lymphoma. The authors provide a comprehensive overview of the evidence linking HCV to these cancers and discuss the potential mechanisms involved. The study also examines the implications of DAA therapy on the management of cancer in HCV-positive patients.

Optimizing Treatment Strategies for HCV-Positive Cancer Patients

This research provides valuable insights into the management of HCV-positive cancer patients. The review emphasizes the importance of considering HCV infection when developing treatment plans for cancer patients, particularly in the context of potential interactions between antiviral therapy and antineoplastic protocols. The findings highlight the need for ongoing research to optimize treatment strategies for this patient population.

Dr.Camel's Conclusion

Imagine a vast desert, where the sands hold secrets and the winds carry tales of both hope and danger. This research delves into the complex relationship between hepatitis C virus infection and the development of non-hepatocellular cancers. The authors, like skilled desert explorers, have meticulously mapped out the intricate pathways linking HCV to these malignancies. Their findings provide valuable insights for navigating the complexities of treating cancer in patients with HCV infection, reminding us that understanding the connections between seemingly disparate aspects of health is crucial for optimal patient care.

Date :
  1. Date Completed 2020-09-21
  2. Date Revised 2020-09-21
Further Info :

Pubmed ID

30983083

DOI: Digital Object Identifier

10.1111/liv.14119

Related Literature

SNS
PICO Info
in preparation
Languages

English

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