Bacterial l-asparaginases for cancer therapy: Current knowledge and future perspectives.

Author: Al-AbodiHiba Riyadh, Al-MarzoqiAli-Hussein, AlghanimiYasemin Khudiar, FattahiAzam, GhasemianAbdolmajid, KadhumSamah Ahmed, Shokouhi MostafaviSeyyed Khalil

Paper Details 
Original Abstract of the Article :
l-Asparaginases hydrolyzing plasma l-asparagine and l-glutamine has attracted tremendous attention in recent years owing to remarkable anticancer properties. This enzyme is efficiently used for acute lymphoblastic leukemia (ALL) and lymphosarcoma and emerged against ALL in children, neoplasia, and s...See full text at original site
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引用元:
https://doi.org/10.1002/jcp.28563

データ提供:米国国立医学図書館(NLM)

Bacterial l-Asparaginases: A New Weapon in the Fight Against Cancer

Cancer, a formidable foe, often leaves patients feeling lost in a vast desert of uncertainty. This study explores the potential of bacterial l-asparaginases, enzymes that break down asparagine and glutamine, as a promising weapon in the fight against cancer. The researchers delve into the mechanisms of action of these enzymes, highlighting their ability to inhibit the growth of cancer cells by depleting essential nutrients. The study also discusses the production of l-asparaginases by various bacteria, including Escherichia coli, Erwinia species, Streptomyces, and Bacillus subtilis, and explores the potential for using these enzymes in cancer therapy.

Finding Hope in the Desert: Exploring New Therapies

This research offers a beacon of hope in the fight against cancer. The study highlights the potential of bacterial l-asparaginases as a valuable tool in cancer treatment. While these enzymes have shown promise, the study underscores the need to address potential side effects, such as hypersensitivity, through further research and development.

Navigating the Desert of Cancer: Exploring New Treatment Options

The study's findings suggest that bacterial l-asparaginases hold promise as a new weapon in the fight against cancer. It's essential to continue exploring the potential of these enzymes, optimizing their production and addressing any associated side effects. Through continuous research and innovation, we can bring hope and relief to those navigating the desert of cancer.

Dr.Camel's Conclusion

This study serves as a reminder that the search for effective cancer therapies is an ongoing journey. Bacterial l-asparaginases offer a promising avenue for exploration, potentially providing a new weapon against this devastating disease.

Date :
  1. Date Completed 2020-05-29
  2. Date Revised 2020-05-29
Further Info :

Pubmed ID

30993718

DOI: Digital Object Identifier

10.1002/jcp.28563

Related Literature

SNS
PICO Info
in preparation
Languages

English

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