Paper Details

  1. Home
  2. Paper Details

Primary debulking surgery vs. interval debulking surgery for advanced ovarian cancer: review of the literature and meta-analysis.

Author: BaioccoErmelinda, BruniSimone, CertelliCamilla, ChiofaloBenito, SperdutiIsabella, VizzaEnrico

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

This systematic review and meta-analysis evaluated the effectiveness of neoadjuvant chemotherapy (NACT) and interval debulking surgery (IDS) compared to primary debulking surgery (PDS) followed by chemotherapy in advanced epithelial ovarian cancer (EOC). While the study did not reveal a clear advantage of NACT or IDS over PDS, it underscored the need for further research to determine the optimal approach for individual patients.
Paper Details　
Original Abstract of the Article :
Epithelial ovarian cancer (EOC) is the seventh most common cancer among women in the world and the leading cause of death from gynecological malignancies. The standard treatment for advanced EOC consists of optimal primary debulking surgery (PDS) associated with an adjuvant chemotherapy. Neoadjuvant...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.23736/S0026-4806.19.06078-6

データ提供：米国国立医学図書館（NLM）

Optimal Debulking Surgery for Advanced Ovarian Cancer

This research explores a crucial aspect of [epithelial ovarian cancer (EOC) management], namely the role of [primary debulking surgery (PDS)] and [interval debulking surgery (IDS)] in advanced EOC. The authors conducted a [systematic review and meta-analysis] of the existing literature to compare the [oncologic and postoperative outcomes] of these surgical approaches. Their findings suggest that [PDS followed by chemotherapy remains the standard treatment] for advanced EOC, with [NACT and IDS showing potential but requiring further investigation].

Debulking Surgery: A Vital Tool in Ovarian Cancer Treatment

The study reaffirms the importance of [debulking surgery] in [improving outcomes for advanced EOC]. The researchers found that [PDS] was associated with [better oncologic outcomes] compared to [NACT and IDS]. However, they also highlight the need for [further research to evaluate the role of NACT and IDS], particularly in specific patient populations.

Navigating the Surgical Landscape: A Balanced Approach

Imagine a desert oasis, where a variety of plants and animals thrive. Similarly, [ovarian cancer treatment] requires a multidisciplinary approach, taking into account both surgical and non-surgical interventions. This research emphasizes the importance of [careful selection of the optimal surgical approach] based on individual patient factors. It's crucial to [consider the unique needs of each patient] and [weigh the potential benefits and risks of different treatment options] in order to achieve the best possible outcomes.

Dr. Camel's Conclusion

This research provides valuable insights into the [current best practices for treating advanced EOC]. While [PDS remains the standard of care], the study underscores the need for [ongoing research] to explore the potential benefits and limitations of [NACT and IDS]. A careful and personalized approach to treatment planning is essential, ensuring that patients receive the most appropriate care based on their individual circumstances. Just as a wise desert traveler chooses the most suitable path based on the terrain, clinicians must navigate the complex landscape of ovarian cancer treatment with precision and compassion.

Date :
  1. Date Completed 2019-07-23
  2. Date Revised 2019-07-23
Further Info :

Pubmed ID

31081304

DOI: Digital Object Identifier

10.23736/S0026-4806.19.06078-6

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.