Cold water extraction of codeine/paracetamol combination products: a case series and literature review.

Author: ArcherJohn R H, DarganPaul I, DinesAlison M, HarnettJames T, WoodDavid M

Paper Details 
Original Abstract of the Article :
<b>Introduction:</b> Tampering with opioid containing medications for use other than their prescribed indication is well documented; however, the published literature has concentrated on stronger, prescription opioids. Less potent opioids, such as codeine, are available without prescription in many...See full text at original site
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引用元:
https://doi.org/10.1080/15563650.2019.1612069

データ提供:米国国立医学図書館(NLM)

Tampered Analgesics: Understanding the Risks

The field of [emergency medicine] is often tasked with managing the consequences of [drug abuse], including the misuse of [opioids]. This study investigates the practice of [cold-water extraction] as a method for tampering with [codeine/paracetamol combination products], readily available over-the-counter in many European countries.

Cold-Water Extraction: A Dangerous Trend

This study highlights the growing concern of [cold-water extraction] for [recreational codeine use] and explores the potential risks associated with this practice. The study identified [seven presentations] in [six patients] who had self-reported [ingestion of cold-water extracted codeine/paracetamol], none of whom developed [paracetamol toxicity]. However, a review of the literature suggests that this method can lead to [significant reduction in recovered paracetamol] and has been linked to [one fatality] and [frequent adverse events, including hospital admission for paracetamol toxicity].

Public Health Implications: Raising Awareness

The study's findings emphasize the need for increased public health awareness regarding the dangers of [cold-water extraction] and other methods of tampering with [nonprescription analgesics]. Educating the public about the potential risks associated with these practices is crucial for preventing [unintentional overdose] and ensuring safe use of these medications.

Dr.Camel's Conclusion

The world of [drug abuse] can be like a vast and unpredictable desert, where the potential for danger lurks around every corner. This study sheds light on the alarming trend of [cold-water extraction] and its associated risks, highlighting the importance of public health education and awareness to prevent harm from tampered medications.

Date :
  1. Date Completed 2020-08-04
  2. Date Revised 2020-12-10
Further Info :

Pubmed ID

31081395

DOI: Digital Object Identifier

10.1080/15563650.2019.1612069

Related Literature

SNS
PICO Info
in preparation
Languages

English

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