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Efficacy and safety of leflunomide in psoriatic arthritis treatment: A single-arm meta-analysis.

Author: DaiQiaoding, XuLiping, YuXiali

Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.

Overview

Leflunomide is an effective and well-tolerated treatment for PsA. 48% of patients experienced a reduction of ≥50% based on PASI scores. 77% of the patients achieved a PsARC response.
Paper Details　
Original Abstract of the Article :
AIM: To systematically assess the clinical efficacy and safety of leflunomide for treating psoriatic arthritis (PsA). METHODS: PubMed, Embase, and Cochrane Library databases were searched until 1 January, 2018, to include relevant studies in this single-arm meta-analysis. Psoriasis improvement was ...See full text at original site
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引用元：
https://doi.org/10.1111/1756-185X.13599

データ提供：米国国立医学図書館（NLM）

Leflunomide: A New Oasis in the Desert of Psoriatic Arthritis Treatment

Psoriatic arthritis (PsA), a complex autoimmune disease, can be a challenging condition to manage. This study explores the efficacy and safety of leflunomide, a medication used to treat PsA. The researchers conducted a single-arm meta-analysis, pooling data from multiple studies to assess the overall effectiveness of leflunomide in treating PsA. Their findings indicate that leflunomide is a promising treatment option for PsA, showing significant improvements in symptoms and quality of life for many patients.

A Beacon of Hope: Leflunomide for Psoriatic Arthritis Treatment

This study provides a glimmer of hope for individuals living with PsA, highlighting the potential benefits of leflunomide treatment. The researchers have successfully demonstrated the effectiveness of leflunomide in reducing symptoms and improving quality of life for many patients with PsA.

Navigating the Treatment Landscape: Choosing the Right Path for PsA

This research emphasizes the importance of considering individual patient needs and preferences when selecting treatment options for PsA. The findings highlight the potential benefits of leflunomide, providing a valuable tool for healthcare professionals to manage this complex condition.

Dr.Camel's Conclusion

This study offers a comprehensive overview of the efficacy and safety of leflunomide in treating PsA, shedding light on its potential benefits and highlighting its role in the management of this complex condition. The findings suggest that leflunomide may be a valuable treatment option for many patients with PsA, offering hope for improved quality of life and symptom control.

Date :
  1. Date Completed 2020-01-29
  2. Date Revised 2020-01-29
Further Info :

Pubmed ID

31134727

DOI: Digital Object Identifier

10.1111/1756-185X.13599

Related Literature

Article Analysis
・Effective treatment of psoriatic arthritis
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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