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Impact of 13-Valent Pneumococcal Conjugate Vaccine on Colonization and Invasive Disease in Cambodian Children.

Author: BatmunkhNyambat, CooperBen S, DayNicholas P J, GouldKatherine A, HeffelfingerJames D, HindsJason, HossainMd Shafiqul, HydeTerri B, LeabPhana, LessaFernanda C, LySokeng, MiliyaThyl, NgounChanpheaktra, OrkVichit, SaoSena, TurnerClaudia, TurnerPaul, WalldorfJenny A

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, U.S. Gov't, P.H.S.Research funding provided by the Public Health Service (PHS).
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

The introduction of the 13-valent pneumococcal conjugate vaccine (PCV13) in Cambodia led to a decrease in vaccine serotype (VT) pneumococcal colonization and disease in children under five years old.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Cambodia introduced the 13-valent pneumococcal conjugate vaccine (PCV13) in January 2015 using a 3 + 0 dosing schedule and no catch-up campaign. We investigated the effects of this introduction on pneumococcal colonization and invasive disease in children aged <5 years. METHODS: There w...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7145996/

データ提供：米国国立医学図書館（NLM）

The Impact of 13-Valent Pneumococcal Conjugate Vaccine (PCV13) on Cambodian Children

This research explores the impact of introducing the 13-valent pneumococcal conjugate vaccine (PCV13) into the immunization schedule in Cambodia. The study investigated the effects of this vaccination program on pneumococcal colonization and invasive disease in children under five years old. Through meticulous analysis of colonization surveys and hospital data, researchers sought to quantify the effectiveness of PCV13 in protecting vulnerable children.

Vaccination: A Protective Oasis in the Desert of Pneumococcal Disease

The findings of this study provide compelling evidence for the effectiveness of PCV13 in reducing pneumococcal disease in Cambodian children. The introduction of PCV13 was associated with significant declines in both vaccine serotype (VT) pneumococcal colonization and invasive disease. These findings underscore the crucial role of vaccination in protecting children from this potentially life-threatening infection.

Shielding Young Ones from Pneumococcal Infections

This research highlights the importance of vaccination programs in protecting children from infectious diseases. The study provides valuable insights into the effectiveness of PCV13 in reducing pneumococcal disease in Cambodian children, advocating for continued efforts to ensure widespread access to this life-saving vaccine.

Dr. Camel's Conclusion

In the vast desert of childhood infectious diseases, PCV13 emerges as a vital oasis, offering protection against pneumococcal infections. This study highlights the effectiveness of vaccination in safeguarding vulnerable children, urging global efforts to ensure access to this life-saving intervention.

Date :
  1. Date Completed 2021-01-06
  2. Date Revised 2023-11-15
Further Info :

Pubmed ID

31175819

DOI: Digital Object Identifier

PMC7145996

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Article Analysis
・Effects of pneumococcal conjugate vaccine (pcv13
SNS
PICO Info
in preparation
Languages

English

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