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Forecasting the critical role of intermittent therapies for the control of bone resorption.

Author: IdreesM, JavedSana, SohailAyesha

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Intermittent administration of parathyroid hormone is more effective than continuous administration for the treatment of osteoporosis. A mathematical model synchronized with the results of meta-analysis can be used to predict drug potency and dosage rates, helping with drug administration and future clinical studies.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Osteoporosis is a chronic metabolic disease characterized by an imbalance of bone resorption and formation, leading to bone fragility and increased susceptibility to fracture. Parathyroid hormone is approved therapy for the treatment of osteoporosis. METHODS: The intermittent therapy of...See full text at original site
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引用元：
https://doi.org/10.1016/j.clinbiomech.2019.04.023

データ提供：米国国立医学図書館（NLM）

Intermittent Therapy: A Strategic Approach to Osteoporosis Treatment

This study delves into the effectiveness of intermittent parathyroid hormone therapy for osteoporosis, a chronic metabolic disease characterized by bone loss. The researchers analyze existing clinical trial data and develop a mathematical model to predict the optimal dosage and frequency of parathyroid hormone administration. Their findings suggest that intermittent therapy is more effective than continuous therapy, highlighting the importance of optimizing treatment strategies for this debilitating disease.

Osteoporosis: Navigating the Shifting Sands of Bone Health

This study underscores the importance of optimizing treatment strategies for osteoporosis, a disease that weakens bones and increases fracture risk. It's like navigating a constantly shifting desert landscape, where finding the right path is crucial for maintaining bone health. The authors provide valuable insights into the effectiveness of intermittent parathyroid hormone therapy, offering a new perspective on managing this challenging disease.

The Power of Intermittent Therapy

This research highlights the potential of intermittent therapy for a wide range of chronic diseases, including osteoporosis. It's like recognizing that the desert environment requires adaptation and flexibility for survival. The authors demonstrate that intermittent parathyroid hormone therapy can be a more effective and efficient approach to managing osteoporosis, offering a new paradigm for treatment.

Dr.Camel's Conclusion

This study provides compelling evidence for the effectiveness of intermittent parathyroid hormone therapy for osteoporosis, highlighting the importance of optimizing treatment strategies for this challenging disease. It's like discovering a hidden oasis in the vast desert of osteoporosis research, offering a more effective and efficient approach to managing this debilitating condition. The authors emphasize the need for continued research and development in this critical area of medicine.

Date :
  1. Date Completed 2020-07-08
  2. Date Revised 2020-07-08
Further Info :

Pubmed ID

31200297

DOI: Digital Object Identifier

10.1016/j.clinbiomech.2019.04.023

Related Literature

Article Analysis
・Effective treatment of osteoporosis
SNS
PICO Info
in preparation
Languages

English

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