Drug-induced endocrine blood pressure elevation.

Author: BeckKatharina R, OdermattAlex, ThompsonGeorge R

Paper Details 
Original Abstract of the Article :
Patients with uncontrolled hypertension are at risk for cardiovascular complications. The majority of them suffers from unidentified forms of hypertension and a fraction has so-called secondary hypertension with an identifiable cause. The patient's medications, its use of certain herbal supplements ...See full text at original site
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引用元:
https://doi.org/10.1016/j.phrs.2019.104311

データ提供:米国国立医学図書館(NLM)

Unveiling the Hidden Causes of Hypertension: A Look at Drugs and Their Endocrine Effects

Navigating the complex landscape of [Hypertension], we encounter a multitude of factors that can contribute to its development. This research delves into the often-overlooked role of medications in driving up blood pressure. By exploring the intricate interplay between drugs and the human endocrine system, this research provides invaluable insights into the potential causes of secondary hypertension. The authors take a comprehensive approach, examining drugs that exert their effects at various levels within the endocrine system, including steroid synthesis and metabolism, mineralocorticoid receptor activity, and the catecholaminergic system. This research serves as a crucial guide for clinicians, reminding them to consider the potential impact of medications on blood pressure, even for seemingly unrelated conditions.

Hidden Factors: Medications as Culprits

The research underscores the importance of considering the potential impact of medications on blood pressure, particularly when faced with cases of uncontrolled hypertension. The study highlights that a significant portion of patients with hypertension suffer from unidentified forms, while a smaller but significant fraction experience secondary hypertension caused by identifiable factors. The authors emphasize the crucial role of medications in driving up blood pressure, even when these drugs are intended to treat seemingly unrelated conditions. This research encourages clinicians to conduct a thorough assessment of a patient's medication history, as this can be a key factor in accurately diagnosing and managing hypertension.

Taking Stock of Medications: A Crucial Step

This research highlights the importance of a comprehensive approach to managing hypertension, particularly when considering the impact of medications. The study emphasizes the need for a careful evaluation of a patient's medication history, taking into account both prescription and over-the-counter drugs, as well as herbal supplements. It's important to remember, as the wise desert nomads say, "Every grain of sand contributes to the vastness of the desert." Similarly, each medication, no matter how seemingly insignificant, can contribute to the overall picture of a patient's health.

Dr.Camel's Conclusion

This research serves as a crucial reminder that the quest for healthy blood pressure requires a multifaceted approach. By delving into the subtle but impactful influence of medications, this study provides valuable insights for clinicians seeking to effectively diagnose and manage hypertension. This research, like the vast desert, holds hidden treasures of knowledge that, when unearthed, can lead to better patient care.

Date :
  1. Date Completed 2021-03-15
  2. Date Revised 2021-03-15
Further Info :

Pubmed ID

31212012

DOI: Digital Object Identifier

10.1016/j.phrs.2019.104311

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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