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Efficacy of High Specific Volume Polysaccharide - A New Type of Dietary Fiber - On Molecular Mechanism of Intestinal Water Metabolism in Rats With Constipation.
Author: CongLiang, DuanLi-Wei, HaoShuhong, LiDong-Fu, SuWei-Ping
Original Abstract of the Article :
BACKGROUND The aim of this study was to evaluate the effects of a new type of dietary fiber - high specific volume polysaccharide (HSVP) - on fecal properties, serum vasoactive intestinal peptide (VIP) concentration, intestinal flora count, and expression of the VIP-cAMP-PKA-AQP3 signaling pathway. ...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6636405/
データ提供:米国国立医学図書館(NLM)
A New Dietary Fiber: High Specific Volume Polysaccharide (HSVP)
Constipation is a common gastrointestinal disorder that can significantly impact quality of life. While various treatments exist, researchers continue to explore new and effective ways to address this condition. This study investigates the effects of a novel dietary fiber, high specific volume polysaccharide (HSVP), on constipation in rats.
HSVP: A Promising Solution for Constipation
The study found that HSVP significantly improved fecal properties in constipated rats, increasing fecal moisture content, reducing hardness, and shortening fecal emptying time. The researchers also found that HSVP influenced the intestinal microbiota and modulated the VIP-cAMP-PKA-AQP3 signaling pathway, suggesting its potential mechanism of action in regulating intestinal water metabolism.
The Role of Dietary Fiber in Digestive Health
This study highlights the importance of dietary fiber in maintaining digestive health. HSVP's ability to improve fecal properties and modulate intestinal signaling pathways suggests its potential as a therapeutic agent for constipation. Just as a desert oasis replenishes travelers with essential water, HSVP can help restore the balance of the digestive system.
Dr. Camel's Conclusion
This study provides compelling evidence for the effectiveness of HSVP in alleviating constipation in rats. HSVP's ability to improve fecal properties and modulate intestinal signaling pathways suggests its potential as a therapeutic agent for this common gastrointestinal disorder. This research reinforces the crucial role of dietary fiber in maintaining digestive health and underscores the importance of exploring new and innovative approaches to addressing constipation.
Date :
- Date Completed 2019-12-11
- Date Revised 2020-02-25
Further Info :
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