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Sex differences in the pharmacology of itch therapies-a narrative review.

Author: KrähenbühlStephan, MuellerSimon M, NavariniAlexander, PfleidererBettina, SchmidYasmin, ThomasZita-Rose Manjaly

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

This review discusses the growing evidence of sex differences in the perception, clinical presentation, and treatment requirements of chronic itch. Further research is needed to understand how sex affects the pharmacology of itch treatments and to develop sex-adapted therapies.
Paper Details　
Original Abstract of the Article :
Chronic itch is the most common skin-related condition, associated with a high psychosocial and economic burden. In recent years, increasing evidence of sex differences in the perception, clinical presentation and treatment requirements of itch points towards potential benefits when using sex-adapte...See full text at original site
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ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1016/j.coph.2019.05.008

データ提供：米国国立医学図書館（NLM）

Sex Differences in Itch: Navigating the Desert of Skin Discomfort

Chronic itch, a relentless discomfort affecting millions, can significantly impact quality of life. This study explores the intriguing topic of sex differences in itch pharmacology, recognizing that sex-specific considerations may be crucial for effective treatment. The research delves into the diverse ways in which the body processes and responds to medications, highlighting potential sex differences in drug absorption, metabolism, elimination, and adverse drug reactions (ADRs). This research underscores the importance of personalized medicine, considering individual patient characteristics to optimize treatment outcomes.

Tailoring Treatment to the Unique Desert Landscape

This research highlights the importance of considering sex differences in the treatment of chronic itch, emphasizing the need for personalized medicine approaches. It's like navigating the diverse landscape of a vast desert, where understanding the unique characteristics of each region is essential for successful navigation. The findings encourage further investigation into sex-specific itch therapies, potentially leading to more effective and personalized treatment strategies.

A New Oasis in the Desert of Itch

This research sheds light on the importance of sex-specific considerations in itch treatment, offering a new perspective on managing this challenging condition. It's like discovering a hidden oasis in the desert of itch, providing relief and hope for those struggling with this persistent discomfort. The findings encourage further investigation into sex-specific itch therapies, potentially leading to more targeted and effective treatment strategies, improving the lives of individuals suffering from chronic itch.

Dr. Camel's Conclusion

This research emphasizes the importance of understanding sex differences in itch pharmacology, offering a new lens through which to view this challenging condition. It's like navigating the vast desert of itch research, seeking personalized solutions for those seeking relief from persistent discomfort. The findings encourage further exploration of sex-specific therapies, potentially leading to more effective and targeted treatment strategies, improving the quality of life for individuals suffering from chronic itch.
Date :
  1. Date Completed 2020-06-19
  2. Date Revised 2020-06-19
Further Info :

Pubmed ID

31299512

DOI: Digital Object Identifier

10.1016/j.coph.2019.05.008

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