A randomized trial of adjuvant endocrine therapy, chemotherapy, and chemoendocrine therapy for operable breast cancer stratified by estrogen receptors.

Author: HisamatsuK, NomuraY, ShinozukaK, TashiroH

Paper Details 
Original Abstract of the Article :
Based on estrogen receptor (ER) status and menopausal status, operable breast cancer (International Union Against Cancer [UICC] Stage I, II, and III) patients were randomized for adjuvant endocrine therapy, chemotherapy, and chemoendocrine therapy, and the effects on the disease-free survival (DFS) ...See full text at original site
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引用元:
https://doi.org/10.1002/1097-0142(19880601)61:11<2168::aid-cncr2820611106>3.0.co;2-f

データ提供:米国国立医学図書館(NLM)

Adjuvant Endocrine Therapy for Breast Cancer

Breast cancer, a formidable foe, has been the subject of intense research and innovation, with scientists and clinicians constantly seeking more effective and personalized treatments. This study delves into the complex world of adjuvant therapy for breast cancer, specifically investigating the effectiveness of endocrine therapy, chemotherapy, and combined chemoendocrine therapy. The researchers, like skilled artisans carefully crafting a mosaic, analyzed the effects of these therapies on the survival and recurrence of breast cancer, seeking to optimize treatment outcomes.

Navigating the Landscape of Breast Cancer Treatment

The study found that endocrine therapy, which targets the hormone estrogen, was equally effective in preventing disease recurrence and improving survival compared to chemotherapy or combined chemoendocrine therapy. This finding, like a desert oasis revealing its hidden treasures, offers valuable insights into the efficacy of different treatment approaches for breast cancer.

Personalized Treatment Strategies

This study underscores the importance of tailoring treatment strategies to individual patient characteristics, such as estrogen receptor status and menopausal status. It's essential to recognize that, just as each desert oasis has its unique characteristics, each patient requires a personalized approach to achieve the best possible outcomes.

Dr. Camel's Conclusion

This study provides a valuable roadmap for treating breast cancer, emphasizing the importance of personalized treatment strategies and recognizing the efficacy of endocrine therapy in certain patient groups. Like a skilled desert traveler choosing the most efficient route, clinicians must carefully consider individual patient factors to optimize treatment outcomes and improve the chances of long-term survival.

Date :
  1. Date Completed 1988-06-21
  2. Date Revised 2019-06-19
Further Info :

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English

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