Efficacy and safety of lasmiditan in patients using concomitant migraine preventive medications: findings from SAMURAI and SPARTAN, two randomized phase 3 trials.

Author: AilaniJessica, BayganiSimin, HundemerHans-Peter, KregeJohn H, LooLi Shen, PortMartha, SchimJack

Paper Details 
Original Abstract of the Article :
OBJECTIVE: To study the efficacy and safety of lasmiditan for acute treatment of migraine in patients using migraine preventive medications. BACKGROUND: While lasmiditan has been proven to be an effective acute treatment for migraine, its effectiveness has not been examined when used concurrently w...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6734212/

データ提供:米国国立医学図書館(NLM)

Lasmiditan for Migraine Treatment: Effectiveness with Preventive Medications

This study explores the effectiveness of lasmiditan, a novel medication for treating acute migraine attacks, in patients also taking migraine preventive medications. The researchers analyzed data from two large, randomized clinical trials, examining the efficacy and safety of lasmiditan in patients using a variety of preventive therapies. The study found that lasmiditan was effective in reducing migraine pain and other symptoms, even in patients using preventive medications. Importantly, the study also found no significant differences in efficacy or safety between patients using and not using preventive therapies, suggesting that lasmiditan can be safely and effectively used in conjunction with a range of migraine preventive medications.

Lasmiditan: A Promising Option for Migraine Relief

This study provides encouraging news for individuals suffering from migraines. It demonstrates that lasmiditan is an effective treatment option for acute migraine attacks, even in patients who are also taking preventive medications. This finding expands the therapeutic options available for migraine patients, potentially leading to improved symptom control and reduced reliance on other medications.

Implications for Migraine Treatment and Patient Care

This research has significant implications for migraine treatment and patient care. It provides clinicians with valuable information regarding the efficacy and safety of lasmiditan in patients using preventive therapies. The study's findings may encourage clinicians to consider lasmiditan as a treatment option for patients with migraines who are also taking preventive medications. It also underscores the importance of personalized treatment approaches to optimize outcomes for individuals suffering from migraines.

Dr.Camel's Conclusion

Like a cool desert breeze providing relief from the scorching sun, lasmiditan offers a promising solution for individuals struggling with migraines. This research highlights the effectiveness of lasmiditan even when used alongside preventive medications, expanding the therapeutic options available for migraine patients. This study serves as a beacon of hope in the battle against migraine headaches, encouraging further research and offering a potential path towards improved symptom control and greater patient well-being.

Date :
  1. Date Completed 2019-11-06
  2. Date Revised 2021-12-04
Further Info :

Pubmed ID

31340760

DOI: Digital Object Identifier

PMC6734212

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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