A Novel Approach of Drug Localization through Development of Polymeric Micellar System Containing Azelastine HCl for Ocular Delivery.

Author: BhattShailendra, DeepAman, DeviSheetal, GuptaSumeet, KumarManish, SainiVipin

Paper Details 
Original Abstract of the Article :
Development of polymeric micelles for the management of allergic conjunctivitis to overcome the limitations of topical installation, such as poor patient compliance, poor stromal permeability, and significant adverse effects, increase precorneal residence time and efficacy, and also control the rele...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7040519/

データ提供:米国国立医学図書館(NLM)

A Novel Approach to Ocular Drug Delivery: Polymeric Micelles

The field of ophthalmology is constantly evolving, seeking innovative ways to deliver medication to the delicate structures of the eye. This study explores the potential of polymeric micelles, tiny carriers that can encapsulate drugs and deliver them directly to the target area. The researchers are looking to overcome the challenges of topical eye drops, which often lead to poor patient compliance, limited drug penetration, and undesirable side effects.

Polymeric Micelles: A Smart Solution for Eye Delivery

The study proposes that polymeric micelles could be a smart solution for delivering azelastine HCl, a medication used to treat allergic conjunctivitis. These tiny carriers could increase precorneal residence time, enhancing the drug's efficacy and allowing for a more controlled release at the target site. Imagine these micelles as miniature delivery trucks, navigating the complex landscape of the eye to precisely deliver their cargo.

A Better Future for Allergic Conjunctivitis Management

This research could lead to improved treatment options for allergic conjunctivitis, offering patients a more effective and comfortable experience. It's a step towards a future where we can address eye problems with greater precision and less discomfort.

Dr.Camel's Conclusion

This study highlights the exciting potential of polymeric micelles as a novel approach to drug delivery in ophthalmology. By providing a more targeted and controlled release mechanism, polymeric micelles could revolutionize the treatment of allergic conjunctivitis. It's a journey into the microscopic world of drug delivery, seeking a better future for eye health.

Date :
  1. Date Completed 2020-01-15
  2. Date Revised 2020-03-15
Further Info :

Pubmed ID

31362666

DOI: Digital Object Identifier

PMC7040519

Related Literature

SNS
PICO Info
in preparation
Languages

English

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