Paper Details
- Home
- Paper Details
Transdermal lipid vesicular delivery of iloperidone: Formulation, in vitro and in vivo evaluation.
Author: BhasinBhavya, LondheVaishali Y
Original Abstract of the Article :
The objective of present study was to develop and evaluate lipid vesicular transdermal system of iloperidone. Liposomes were prepared successfully using thin film hydration method. With aim of enhancing permeation, cholesterol from liposomes was replaced with transcutol to give PEVs. Liposomes and P...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1016/j.colsurfb.2019.110409
データ提供:米国国立医学図書館(NLM)
Transdermal Delivery of Iloperidone: A New Oasis in Drug Delivery
This research delves into the intriguing world of transdermal drug delivery, exploring innovative ways to deliver medications through the skin. It’s like finding a new oasis that provides sustenance and relief in a unique and effective way. The study focuses on developing a transdermal system for iloperidone, an antipsychotic medication. This is like finding a new oasis that offers a novel way to deliver a vital resource.The researchers successfully formulated lipid vesicles, specifically liposomes and phospholipid-ethylenediamine vesicles (PEVs), to enhance the delivery of iloperidone. The study found that both liposomes and PEVs showed better skin deposition and permeation compared to plain iloperidone. This is like finding an oasis that provides a more efficient way to absorb nutrients and water. In vivo studies demonstrated that the PEV-loaded gel system showed significantly higher bioavailability compared to oral iloperidone or the gel without vesicles. This is like finding an oasis that not only provides sustenance but also enhances the body’s ability to utilize those resources.
A New Oasis for Drug Delivery
This study suggests that transdermal delivery systems may offer a promising approach for delivering iloperidone and potentially other medications. It’s like discovering a new oasis that offers a more efficient and effective way to deliver resources. This approach could potentially improve patient adherence and reduce the risk of side effects associated with oral administration.Living Well with Iloperidone
If you are taking iloperidone, it’s important to talk to your doctor about the best way to take your medication. This is like finding a reliable guide to navigate the desert and find the right oasis for your needs. Transdermal delivery may offer a new and potentially beneficial option for some patients.Dr.Camel's Conclusion
This research showcases the ingenuity of scientists in finding new and innovative ways to deliver medications. It’s like discovering a new oasis in a vast and arid landscape. The transdermal delivery of iloperidone may offer a more convenient and effective way to treat patients, potentially improving their overall well-being.Date :
- Date Completed 2020-03-16
- Date Revised 2020-03-16
Further Info :
Related Literature
English
This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.