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Effects of Highly Active Antiretroviral Therapy on Albuminuria in HIVinfected Persons.
Author: AdebisiSimeon Adelani, AdedejiNife Olamide, AdedejiTewogbade Adeoye
Original Abstract of the Article :
BACKGROUND: Highly active antiretroviral therapy (HAART), especially tenofovir DFcontaining regimens, has been implicated in albuminuria. OBJECTIVE: We prospectively evaluated the effects of HAART on albumin-to-creatinine ratios (ACRs) in antiretroviral-naïve HIV-infected individuals. METHODS: One...See full text at original site
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引用元:
https://doi.org/10.2174/1871526519666190807155025
データ提供:米国国立医学図書館(NLM)
The Impact of HIV Treatment on Kidney Health
The fight against HIV is an ongoing quest, much like a determined camel traversing the vast desert in search of a distant oasis. Highly active antiretroviral therapy (HAART), a vital weapon in this battle, has revolutionized the treatment of HIV, bringing hope and extending lives. However, researchers are continuously exploring the nuances of these medications, like a meticulous traveler mapping the intricacies of a complex landscape. This study focused on the potential effects of HAART on kidney function, specifically examining the impact on albuminuria, a sign of kidney damage.Navigating the Complex Terrain of HAART
This study evaluated the effects of different HAART regimens on albuminuria in newly diagnosed HIV-infected individuals. The researchers found that HAART, particularly regimens containing tenofovir DF, could have a mixed impact on albuminuria. Some individuals showed improvement, while others experienced a worsening of their kidney function, much like a desert traveler encountering both fertile oases and treacherous sandstorms on their journey. However, the study also discovered that specific regimens like Zidovudine/Lamivudine/Nevirapine (ZDV/3TC/NVP) were associated with earlier resolution of microalbuminuria, suggesting that certain treatment approaches could minimize the risk of kidney damage.Understanding the Balancing Act
This research underscores the importance of carefully managing HIV treatment, paying close attention to potential side effects on kidney health. It's like a wise desert traveler understanding the delicate balance between preserving resources and seeking out vital water sources. The study emphasizes the need for regular monitoring of kidney function in HIV-infected individuals, particularly those receiving HAART, to ensure optimal treatment outcomes and minimize the risk of complications.Dr.Camel's Conclusion
This study highlights the complex interplay between HIV treatment and kidney health, a topic as intricate as the shifting sands of a desert landscape. While HAART has revolutionized HIV care, its impact on kidney function requires careful monitoring and personalized treatment strategies. This research serves as a valuable roadmap for optimizing treatment regimens, ensuring the long-term well-being of HIV-infected individuals.Date :
- Date Completed 2021-04-16
- Date Revised 2021-04-16
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