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Synergistic Effects of Anionic/Cationic Dendrimers and Levofloxacin on Antibacterial Activities.
Author: AppelhansDietmar, BryszewskaMaria, LisowskaKatarzyna, MajoralJean Pierre, WrońskaNatalia
Original Abstract of the Article :
Despite the numerous studies on dendrimers for biomedical applications, the antibacterial activity of anionic phosphorus dendrimers has not been explored. In our research, we evaluated the antibacterial activity of modified polycationic and polyanionic dendrimers in combination with levofloxacin (LV...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6719981/
データ提供:米国国立医学図書館(NLM)
Dendrimer-Based Drug Delivery: Synergistic Effects on Antibacterial Activity
The emergence of antibiotic resistance poses a significant threat to global health. This study explores the potential of dendrimer-based drug delivery systems to enhance the antibacterial activity of levofloxacin (LVFX), a fluoroquinolone antibiotic. The researchers evaluated the antibacterial activity of modified polycationic and polyanionic dendrimers in combination with LVFX against both Gram-negative and Gram-positive bacteria. They found that a combination of dendrimers and LVFX exhibited synergistic effects, particularly against Gram-negative bacteria. This research suggests that dendrimers could be a promising approach for overcoming antibiotic resistance and improving drug delivery.Dendrimer-Based Drug Delivery: A Potential Solution for Antibiotic Resistance
This study offers a promising solution to the growing challenge of antibiotic resistance. The researchers have demonstrated that dendrimers can effectively enhance the antibacterial activity of levofloxacin (LVFX), particularly against Gram-negative bacteria. This finding suggests that dendrimer-based drug delivery systems could be a valuable approach for overcoming antibiotic resistance and improving treatment outcomes.The Future of Antibiotic Therapy: Embracing Innovative Delivery Strategies
This research highlights the importance of embracing innovative drug delivery strategies to combat antibiotic resistance. The researchers' findings underscore the potential of dendrimers as a promising approach to enhance the effectiveness of antibiotics and improve treatment outcomes. This innovative approach offers hope for a future where antibiotic resistance is effectively managed and bacterial infections are effectively treated.Dr.Camel's Conclusion
Like a desert traveler discovering a new source of water in a parched land, this research offers a promising solution to the challenge of antibiotic resistance. The researchers' findings suggest that dendrimer-based drug delivery systems could be a valuable approach for enhancing the effectiveness of antibiotics and combating bacterial infections. This innovative approach offers hope for a future where antibiotic resistance is effectively addressed and bacterial infections are effectively managed.Date :
- Date Completed 2020-01-08
- Date Revised 2020-02-25
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