Case report series of a novel application of neostigmine to successfully relieve refractory ileus status post-pediatric orthotopic liver transplantation.

Author: BalakrishnanBinod, HongJohnny C, PetersenPamela C, VitolaBernadette

Paper Details 
Original Abstract of the Article :
Post-operative ileus is common after abdominal surgeries. Children undergoing liver transplant are at increased risk of ileus for various reasons including multiple abdominal procedures and use of narcotic medications. Ileus can lead to abdominal compartment syndrome and compromise the integrity of ...See full text at original site
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引用元:
https://doi.org/10.1111/petr.13564

データ提供:米国国立医学図書館(NLM)

Neostigmine for Refractory Ileus: A Desert Oasis in a Sea of Troubles

Post-operative ileus, a condition characterized by intestinal paralysis, can be a debilitating complication, like a desert traveler stranded without water. This study, like a well-placed oasis in this medical desert, examines the effectiveness of neostigmine in treating refractory ileus in pediatric patients after liver transplantation. The researchers, like seasoned desert guides, explored this new treatment option in a bid to find relief for these vulnerable patients.

A New Path to Recovery: Neostigmine's Promising Results

This study, like a trailblazing expedition, reveals that neostigmine, when used as a continuous infusion, may offer a safe and effective treatment for refractory ileus in pediatric patients following liver transplantation. The findings suggest that neostigmine can help alleviate symptoms such as abdominal distension and promote the passage of gas and stool, facilitating a quicker and more comfortable recovery for these patients.

A Beacon of Hope: Navigating the Challenges

The study's findings offer a beacon of hope for pediatric patients struggling with refractory ileus after liver transplantation. It highlights the importance of exploring alternative treatment options when traditional methods prove ineffective. The research underscores the need for further investigation to fully understand the long-term effects and potential benefits of neostigmine in this context.

Dr. Camel's Conclusion

Refractory ileus after liver transplantation can be a challenging condition, like a desert traveler facing a relentless sandstorm. This study reveals that neostigmine, a new oasis of treatment, may offer a safe and effective solution for these vulnerable patients. The findings highlight the importance of exploring new therapies to address the complexities of post-operative ileus and improve outcomes for pediatric liver transplant recipients.
Date :
  1. Date Completed 2020-08-25
  2. Date Revised 2020-08-25
Further Info :

Pubmed ID

31407849

DOI: Digital Object Identifier

10.1111/petr.13564

Related Literature

SNS
PICO Info
in preparation
Languages

English

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