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Magnesium hydroxide as a complementary aluminium-free phosphate binder to moderate doses of oral calcium in uraemic patients on chronic haemodialysis: lack of deleterious effect on bone mineralisation.

Author: AbdulmassihZ, BelbrikS, CohemsolalM, HocineC, LeflonP, MarieA, MorinièreP, RocheD, VinatierI, WesteelP F

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Magnesium hydroxide was effective in controlling hyperphosphataemia without hyperaluminaemia in 20 haemodialysed patients.
Paper Details　
Original Abstract of the Article :
To control hyperphosphataemia without hyperaluminaemia, A1(OH)3, which was given in addition to high doses of oral calcium, was replaced by Mg(OH)2 for 6 months in 20 haemodialysed patients and for 20 months in 12. The treatment during the control period was 110 +/- 91 mmol/day of oral calcium eleme...See full text at original site
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引用元：
https://doi.org/10.1093/oxfordjournals.ndt.a091722

データ提供：米国国立医学図書館（NLM）

Magnesium Hydroxide: A Safe and Effective Alternative Phosphate Binder in Hemodialysis Patients

The management of hyperphosphatemia in patients on chronic hemodialysis presents a unique challenge for physicians. This study investigates the safety and efficacy of magnesium hydroxide (Mg(OH)2) as a phosphate binder in patients with chronic kidney disease. The authors aimed to control hyperphosphatemia without introducing the risk of hyperaluminaemia, a common complication associated with aluminum hydroxide (A1(OH)3). The study involved a group of haemodialysed patients who received Mg(OH)2 in place of A1(OH)3 for a period of 6 to 20 months. The results were promising: Mg(OH)2 effectively controlled hyperphosphatemia, while maintaining stable levels of calcium, aluminum, alkaline phosphatase, and parathyroid hormone (PTH). The study also highlighted that Mg(OH)2 did not have any adverse effects on bone mineralization.

Magnesium Hydroxide: A Safe and Effective Phosphate Binder

The findings of this study suggest that Mg(OH)2 is a safe and effective phosphate binder in haemodialysed patients. Its ability to control hyperphosphatemia without negatively impacting bone health makes it a valuable tool for managing this condition.

Magnesium Hydroxide: A Boon for Hemodialysis Patients

The results of this study provide valuable insights for healthcare professionals who manage patients on chronic hemodialysis. Magnesium hydroxide offers a safe and effective alternative to aluminum hydroxide for phosphate binding, potentially improving the long-term health of these patients.

Dr.Camel's Conclusion

Magnesium hydroxide proves to be a safe and effective phosphate binder, providing a valuable alternative for patients undergoing hemodialysis. This study sheds light on the importance of exploring alternative treatment options for managing complex medical conditions.

Date :
  1. Date Completed 1989-03-14
  2. Date Revised 2019-05-10
Further Info :

Pubmed ID

3146723

DOI: Digital Object Identifier

10.1093/oxfordjournals.ndt.a091722

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Languages

English

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