Paper Details

  1. Home
  2. Paper Details

Plecanatide for the treatment of chronic idiopathic constipation in adult patients.

Author: BassottiGabrio, BelliniMassimo, Usai SattaPaolo

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

This review examines the effectiveness and safety of plecanatide, a guanylate cyclase-C agonist, in treating chronic idiopathic constipation (CIC). Clinical studies show that plecanatide is significantly more effective than placebo in reducing constipation symptoms and improving quality of life.
Paper Details　
Original Abstract of the Article :
<b>Introduction</b>. Chronic idiopathic constipation (CIC) is a functional gastrointestinal disorder that is associated with an increased healthcare cost and an abnormally poor quality of life. Plecanatide is a natural analog to the peptide agonist of the guanylate cyclase-C (GC-C) receptor, urogua...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1080/17512433.2019.1670057

データ提供：米国国立医学図書館（NLM）

A New Hope for Chronic Constipation: Plecanatide

Imagine a desert traveler struggling to navigate a path through a treacherous sandstorm. This research offers a new approach to addressing a common, yet often debilitating, condition: chronic idiopathic constipation (CIC).

Plecanatide: A Novel Treatment for CIC

The study focuses on plecanatide, a natural analog of uroguanylin, a peptide agonist of the guanylate cyclase-C (GC-C) receptor. Plecanatide works by increasing fluid secretion in the intestines, promoting easier bowel movements.

Promising Results and Potential Benefits

Studies have shown that plecanatide is significantly more effective than placebo in reducing CIC severity, straining, and improving overall quality of life. This promising new agent offers a potential solution for patients who have not responded to conventional treatments.

Dr. Camel's Conclusion

This research suggests that plecanatide could be a game-changer for patients suffering from CIC. Like finding a refreshing oasis in a vast, arid desert, plecanatide offers a potential path towards relief and improved quality of life for individuals with this challenging condition.

Date :
  1. Date Completed 2019-11-22
  2. Date Revised 2019-11-22
Further Info :

Pubmed ID

31575291

DOI: Digital Object Identifier

10.1080/17512433.2019.1670057

Related Literature

Article Analysis
・Effects of plecanatide
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.