The efficacy and safety of permethrin 2.5% with tea tree oil gel on rosacea treatment: A double-blind, controlled clinical trial.

Author: AsgharianRamin, AzizianZahra, EbneyaminElnaz, MansouriParvin, QomiMahnaz, RajabiMehdi

Paper Details 
Original Abstract of the Article :
BACKGROUND: Rosacea is a chronic skin condition that typically affects the face and it results in redness and inflammation. The main risk factors of this disease are Demodex folliculorum, living in the pilosebaceous units. AIMS: To evaluate the efficacy and safty of permethrin 2.5% in combination w...See full text at original site
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引用元:
https://doi.org/10.1111/jocd.13177

データ提供:米国国立医学図書館(NLM)

Permethrin 2.5% with Tea Tree Oil: A New Approach to Rosacea Treatment?

Rosacea is a stubborn skin condition that affects millions of people. The researchers in this study decided to take a closer look at the role of Demodex folliculorum, tiny mites that live in hair follicles, in causing rosacea. They conducted a double-blind, randomized clinical trial to evaluate the efficacy of permethrin 2.5% with tea tree oil (TTO) gel in treating rosacea. Their investigation focused on the impact of this topical gel on Demodex density and the overall clinical manifestations of rosacea.

Positive Results: A Beacon of Hope for Rosacea Sufferers

The findings of this study are quite encouraging! The research revealed that permethrin 2.5% with TTO gel demonstrated a significant reduction in Demodex density and noticeable improvement in clinical features of rosacea. The improvement was observed in papules, pustules, and nontransient erythema. The researchers found a significant improvement in burning, stinging, and dry appearance, with itching being significantly less than in the placebo group. These results suggest that this topical gel might be a promising treatment option for rosacea.

A New Path to Clear Skin: Balancing Benefits and Risks

While these results are promising, it's important to note that permethrin 2.5% with TTO gel is not a magic cure for rosacea. It is essential to consult with a dermatologist to determine if this treatment is appropriate for you and to discuss potential side effects. The researchers found that this topical gel was safe for most patients, but they also noted that some patients experienced itching. Just like a desert traveler needs to be mindful of the environment, so must individuals with rosacea be aware of potential side effects.

Dr.Camel's Conclusion

Rosacea, like the relentless sun in a desert, can be a real nuisance. But, just like a desert oasis offers relief, this study has shown that permethrin 2.5% with TTO gel could be a new oasis for rosacea sufferers. It's a promising approach, but it's crucial to consult with a dermatologist to determine if it's right for you. Just like a wise camel chooses its path carefully, so must those with rosacea approach treatment with caution and informed decision-making.

Date :
  1. Date Completed 2021-02-08
  2. Date Revised 2021-02-08
Further Info :

Pubmed ID

31613050

DOI: Digital Object Identifier

10.1111/jocd.13177

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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