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Neurobehavioral Consequences Associated with Long Term Tramadol Utilization and Pathological Mechanisms.
Author: ChawlaPooja, RajKhadga, SinghShamsher
Original Abstract of the Article :
Tramadol is a synthetic analog of codeine used to treat pain of moderate to severe intensity and is reported to have neurotoxic potential. At therapeutic dose, tramadol does not cause major side effects in comparison to other opioid analgesics, and is useful for the management of neurological proble...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.2174/1871527318666191112124435
データ提供:米国国立医学図書館(NLM)
Long-Term Tramadol Use: A Potential Path to Neurobehavioral Complications
Tramadol, a pain reliever commonly used for moderate to severe pain, has been a subject of increasing scrutiny due to its potential neurotoxic effects. This research explores the long-term consequences of tramadol use on the nervous system, delving into its association with various neurological disorders. The study highlights that while tramadol offers benefits for pain management and may even help with anxiety and depression, its extended use can lead to a range of neurological complications, including seizures, serotonin syndrome, Alzheimer's disease, and Parkinson's disease. The authors delve into the potential mechanisms underlying these complications, including tramadol's influence on neurotransmitters like serotonin and dopamine, as well as its impact on cellular signaling pathways involved in learning and memory.
Navigating the Labyrinth of Tramadol's Neurological Effects
This research emphasizes the importance of understanding the potential risks associated with long-term tramadol use. The findings point to the need for careful monitoring and assessment of patients who rely on tramadol for pain relief, particularly regarding the emergence of neurological symptoms.
Making Informed Decisions About Pain Management
The study's findings underscore the need for informed decision-making when it comes to pain management. While tramadol can be an effective tool for pain relief, its potential long-term consequences should be carefully considered, especially in individuals with pre-existing neurological conditions or those who require prolonged treatment. Consult your healthcare provider for guidance on appropriate pain management strategies.
Dr. Camel's Conclusion
Tramadol's journey through the human body is a complex one, with both therapeutic benefits and potential neurological side effects. Just like a camel navigating a winding desert path, understanding the intricacies of tramadol's impact on the nervous system is crucial for making informed decisions about pain management.
Date :
- Date Completed 2020-10-13
- Date Revised 2020-10-13
Further Info :
Related Literature
English
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