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Oral amoxicillin and amoxicillin-clavulanic acid: properties, indications and usage.

Author: BielickiJ, ClementsM N, Frimodt-MøllerN, HuttnerA, MoutonJ W, MullerA E, PaccaudJ-P

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Amoxicillin alone is often a preferred choice over amoxicillin-clavulanic acid for treating infections, as clavulanic acid can limit the maximum daily dose of amoxicillin and is associated with more gastrointestinal side effects. More research is needed on heat stability, pharmacodynamic effects, and resistance emergence.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Amoxicillin has been in use since the 1970s; it is the most widely used penicillin both alone and in combination with the β-lactamase clavulanic acid. OBJECTIVES: In this narrative review, we re-examine the properties of oral amoxicillin and clavulanic acid and provide guidance on their...See full text at original site
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引用元：
https://doi.org/10.1016/j.cmi.2019.11.028

データ提供：米国国立医学図書館（NLM）

Amoxicillin and Amoxicillin-Clavulanate: Properties, Indications, and Usage

This research examines the properties, indications, and usage of amoxicillin and amoxicillin-clavulanate, two commonly used antibiotics. It’s like exploring a vast desert pharmacy, understanding the different ingredients and their effects. Amoxicillin is a penicillin antibiotic, while amoxicillin-clavulanate is a combination of amoxicillin and clavulanic acid, a β-lactamase inhibitor that helps amoxicillin work more effectively. The researchers argue that amoxicillin alone may be a suitable treatment for many infections, emphasizing the importance of choosing the right antibiotic for the specific condition.

Choosing the Right Antibiotic: A Wise Decision

The study highlights the potential overuse of amoxicillin-clavulanate, suggesting that amoxicillin alone could be sufficient for treating various infections. It’s like using a specific tool for a particular job – we don’t need to use a sledgehammer for every task. This emphasizes the importance of appropriate antibiotic use, not only for treating infections effectively but also for preventing the development of antibiotic resistance.

Antibiotic Awareness

Remember, antibiotics are powerful tools, but they should be used wisely and only when necessary. It’s like navigating a treacherous desert route: choosing the wrong path can lead to unwanted consequences. If you are experiencing symptoms of an infection, consult a doctor for proper diagnosis and treatment.

Dr.Camel's Conclusion

This study provides valuable insights into the appropriate use of antibiotics, highlighting the need for careful consideration of their properties and indications. It’s like navigating a vast desert landscape: understanding the terrain and choosing the right tools are crucial for a successful journey.

Date :
  1. Date Completed 2021-01-28
  2. Date Revised 2021-01-28
Further Info :

Pubmed ID

31811919

DOI: Digital Object Identifier

10.1016/j.cmi.2019.11.028

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Article Analysis
・Side Effects of amoxicillin and clavulanic acid
SNS
PICO Info
in preparation
Languages

English

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