The Use of Inhaled N-Acetylcysteine for Laryngopharyngeal Reflux Disease: A Randomized Controlled Trial.

Author: ChoiIck Soo, JoYong Seok, SoYoon Kyoung

Paper Details 
Original Abstract of the Article :
Proton pump inhibitors (PPIs) are the mainstay of the medical treatment for laryngopharyngeal reflux disease (LPRD). However, extraesophageal symptoms of LPRD, such as globus, are often refractory to PPI treatment. Many kinds of adjunctive medications have been attempted to address those refractory ...See full text at original site
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引用元:
https://doi.org/10.1016/j.jvoice.2019.11.017

データ提供:米国国立医学図書館(NLM)

Inhaled N-Acetylcysteine: A New Approach to LPRD?

The treatment of [laryngopharyngeal reflux disease (LPRD)] often involves a multi-pronged approach. This study explores the potential of [inhaled N-acetylcysteine (NAC)] as an adjunct therapy to the mainstay treatment, [proton pump inhibitors (PPIs)], for those experiencing [globus sensation], a common symptom of LPRD. Imagine a camel caravan carefully navigating a winding path, each member relying on a combination of tools and strategies to reach their destination.

Searching for a Synergistic Solution

This research investigates whether inhaled NAC, a mucolytic agent, could offer additional relief to patients with LPRD who are not fully responding to PPIs. It's like seeking out a hidden spring of healing in the heart of the desert, hoping to find a source of rejuvenation. The study is designed to determine if the combination of NAC and PPIs can achieve greater success than PPIs alone.

Potential for Enhanced Relief

The results of this study could provide valuable insights into the potential of inhaled NAC as a valuable tool for managing LPRD symptoms. If successful, it could offer a new avenue for relief for those struggling with globus sensation and other persistent symptoms. Like a desert oasis offering respite from the harsh elements, NAC could provide a much-needed source of comfort for those affected by LPRD.

Dr.Camel's Conclusion

This research delves into the world of LPRD, exploring the potential for inhaled NAC to offer additional relief to those struggling with persistent symptoms. It's a testament to the ongoing search for better treatments and solutions in the challenging landscape of chronic health conditions.

Date :
  1. Date Completed 2021-08-16
  2. Date Revised 2021-08-16
Further Info :

Pubmed ID

31848062

DOI: Digital Object Identifier

10.1016/j.jvoice.2019.11.017

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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