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RNA-based therapeutics for colorectal cancer: Updates and future directions.

Author: GuoBin, LiuJingwen

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, N.I.H., ExtramuralResearch funding provided by the NIH to external research institutions and researchers.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

RNA-based therapies show potential for treating colorectal cancer (CRC). This abstract discusses how RNA interference, antisense oligonucleotides, and other RNA-based approaches can be used to treat CRC, addressing issues like multidrug resistance and side effects of traditional treatments.
Paper Details　
Original Abstract of the Article :
Colorectal cancer (CRC) is one of the most common causes of cancer death worldwide. While standard chemotherapy and new targeted therapy have been improved recently, problems such as multidrug resistance (MDR) and severe side effects remain unresolved. RNAs are essential to all biological processes ...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/31866285

データ提供：米国国立医学図書館（NLM）

RNA-Based Therapeutics: A New Frontier in Colorectal Cancer Treatment

This review article explores the potential of RNA-based therapies in the fight against colorectal cancer (CRC). The authors discuss the advantages of RNA-based therapeutics, such as [high specificity], [high potency], and [low toxicity]. They highlight recent advances in the field and discuss ongoing clinical trials involving RNA-based treatments for CRC. This comprehensive overview sheds light on the promising future of RNA-based therapeutics in tackling this challenging disease.

Targeting the Root of the Problem: RNA Therapeutics for CRC

This review emphasizes the potential of RNA-based therapies to address the genetic underpinnings of CRC. By targeting specific RNA molecules involved in cancer development and progression, these therapies offer a novel approach to treating CRC, potentially overcoming limitations of conventional chemotherapy.

Hope for the Future: RNA Therapeutics and Personalized Medicine

The development of RNA-based therapies represents a significant step forward in personalized medicine. By targeting specific genetic alterations in individual patients, these therapies hold the potential for more effective and personalized treatment of CRC, potentially improving treatment outcomes and quality of life for patients.

Dr.Camel's Conclusion

Just as a desert traveler relies on their intuition and knowledge to navigate a vast and challenging landscape, researchers are exploring new frontiers in cancer treatment. RNA-based therapies offer a promising approach to fighting CRC, potentially revolutionizing the way we treat this disease.

Date :
  1. Date Completed 2020-12-31
  2. Date Revised 2021-02-01
Further Info :

Pubmed ID

31866285

DOI: Digital Object Identifier

NIHMS1548078

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Languages

English

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