Paper Details 
Original Abstract of the Article :
UNLABELLED: The findings and conclusions in this report are those of the authors and do not necessarily represent the official positon of the Centers for Disease Control and Prevention. BACKGROUND: Continued indirect effects provided by the childhood pneumococcal conjugate vaccine (13-valent pneumo...See full text at original site
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引用元:
https://doi.org/10.1016/j.vaccine.2019.12.029

データ提供:米国国立医学図書館(NLM)

The Cost of Protection: Pneumococcal Vaccination in Adults

The field of public health is constantly evolving, much like the shifting sands of the desert. This study dives into the ongoing debate about the cost-effectiveness of pneumococcal vaccination in adults, particularly in light of the indirect protection provided by childhood vaccination programs. The researchers employed a probabilistic model to analyze the benefits of continuing to recommend the pneumococcal conjugate vaccine (PCV13) at age 65, taking into account the impact of childhood vaccination on disease incidence in adults.

A Balancing Act: Cost vs. Benefit

The findings reveal a fascinating dynamic. The cost-effectiveness of continuing the PCV13 recommendation at age 65 has significantly increased due to the indirect effects of childhood vaccination. This is a bit like a camel caravan crossing the desert: the initial investment in protecting the young camels creates a ripple effect, reducing the need for further investment in the older ones. However, the study also highlights a potential downside: If the PCV13 doesn't provide sufficient protection against certain serotypes of pneumococcus, the cost per quality-adjusted life year (QALY) gained becomes even higher.

Making Informed Decisions: A Desert of Choices

This research provides valuable insight for healthcare decision-makers. It underscores the importance of balancing the costs and benefits of vaccination programs, especially in the context of evolving disease dynamics. The study also reinforces the need for ongoing monitoring of vaccine efficacy and disease incidence to ensure that public health strategies remain optimal. As a desert wanderer, I always appreciate the value of a good map, and this research is like a roadmap for navigating the complex world of public health.

Dr. Camel's Conclusion

The cost-effectiveness of pneumococcal vaccination in adults is a complex issue, influenced by factors such as the impact of childhood vaccination programs and the changing nature of the disease. This study provides valuable insights into the evolving landscape of this public health concern, highlighting the importance of evidence-based decision-making and ongoing monitoring of vaccine efficacy.

Date :
  1. Date Completed 2021-03-08
  2. Date Revised 2021-03-08
Further Info :

Pubmed ID

31889609

DOI: Digital Object Identifier

10.1016/j.vaccine.2019.12.029

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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