5-Nitroimidazole refractory giardiasis is common in Matanzas, Cuba and effectively treated by secnidazole plus high-dose mebendazole or quinacrine: a prospective observational cohort study.

Author: BritoK, CañeteR, HerreraE, KofoedP-E, NodaA L, RodríguezM, UrsingJ

Paper Details 
Original Abstract of the Article :
OBJECTIVE: To evaluate the effectiveness and tolerability of secnidazole combined with high-dose mebendazole for treatment of 5-nitroimidazole-resistant giardiasis. METHOD: Adults with microscopically verified Giardia intestinalis monoinfection attending a secondary level hospital in Matanzas City,...See full text at original site
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引用元:
https://doi.org/10.1016/j.cmi.2019.12.017

データ提供:米国国立医学図書館(NLM)

Giardiasis: A Persistent Desert Storm

Giardiasis, a parasitic infection that can cause intestinal distress, can be a challenging condition to treat, particularly when it becomes resistant to standard medications. This study, like a team of researchers seeking to conquer a persistent desert storm, investigates the effectiveness of a new treatment strategy for 5-nitroimidazole-refractory giardiasis.

Finding a New Solution

The researchers, like resourceful explorers, found that secnidazole combined with high-dose mebendazole was highly effective in treating 5-nitroimidazole-refractory giardiasis. This promising finding suggests that this combination therapy may provide a viable alternative for patients who have not responded to standard treatment. It’s like discovering a new source of water in a parched desert – this research offers a potential solution to a persistent problem.

Fighting Back Against Infection

This study highlights the importance of being aware of the potential for drug resistance in Giardia infections. If standard treatments are not effective, consulting with your healthcare provider to explore alternative options is crucial. It’s like being prepared for a sandstorm in the desert – being proactive and adaptable can help you overcome the challenges of infection.

Dr.Camel's Conclusion

This study offers a valuable insight into the treatment of 5-nitroimidazole-refractory giardiasis. The findings suggest that secnidazole combined with high-dose mebendazole may be an effective alternative for patients who have not responded to standard therapy. It’s like finding a new path through a familiar desert landscape – this research helps us to navigate the challenges of infection with greater knowledge and effectiveness.

Date :
  1. Date Completed 2021-02-08
  2. Date Revised 2021-02-08
Further Info :

Pubmed ID

31901492

DOI: Digital Object Identifier

10.1016/j.cmi.2019.12.017

Related Literature

SNS
PICO Info
in preparation
Languages

English

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