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Treatment-to-Target With Apremilast in Psoriatic Arthritis: The Probability of Achieving Targets and Comprehensive Control of Disease Manifestations.

Author: BehrensFrank, BrunoriMichele, CoatesLaura C, GladmanDafna D, GueretteBenoit, KavanaughArthur, McInnesIain, MeasePhilip J, OgdieAlexis, QueiroRubén, SmolenJosef S, TengLichen

Clinical Trial, Phase IIIA Phase III trial is a trial that further rigorously verifies the efficacy and safety of a new drug or treatment, whose efficacy and safety have been confirmed in a Phase II trial, in a large number of patients, and evaluates whether it is superior to existing treatments.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This study evaluated the probability of achieving remission or low disease activity (LDA) with apremilast in treating psoriatic arthritis (PsA), considering different disease activity categories and responses in various domains of PsA.
Paper Details　
Original Abstract of the Article :
The present study was undertaken to evaluate the probability of achieving the Clinical Disease Activity Index for Psoriatic Arthritis (cDAPSA) treatment targets of remission or low disease activity (LDA) with apremilast based on disease activity categories and corresponding responses in arthritis an...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7317912/

データ提供：米国国立医学図書館（NLM）

Apremilast: A Treatment-to-Target Approach for Psoriatic Arthritis

Psoriatic arthritis (PsA) is a chronic inflammatory condition that affects the joints and skin. This study examines the effectiveness of apremilast, a medication used to treat PsA, in achieving treatment targets based on the Clinical Disease Activity Index for Psoriatic Arthritis (cDAPSA). The research findings provide insights into the probability of achieving remission or low disease activity (LDA) with apremilast, highlighting its potential as a treatment-to-target approach for PsA.

Apremilast: A Guiding Star in the Desert of Psoriatic Arthritis

Imagine apremilast as a guiding star in the vast desert of PsA, helping patients navigate the challenges of this chronic inflammatory condition. This research explores the effectiveness of apremilast in achieving treatment targets based on the cDAPSA, highlighting its potential to guide treatment strategies toward achieving meaningful clinical outcomes.

Managing Psoriatic Arthritis: Choosing the Right Treatment and Monitoring Progress

PsA can significantly impact a patient's quality of life, making effective treatment essential. This study underscores the importance of a treatment-to-target approach, using tools like the cDAPSA to monitor progress and make informed decisions about treatment strategies. It emphasizes the need for close collaboration between patients and healthcare providers to achieve optimal outcomes.

Dr.Camel's Conclusion

This study highlights the potential of apremilast as a treatment-to-target approach for PsA, emphasizing the importance of using the cDAPSA to monitor progress and guide treatment decisions. The research findings offer hope for achieving meaningful clinical outcomes and improving the lives of individuals living with PsA.

Date :
  1. Date Completed 2020-10-02
  2. Date Revised 2021-02-03
Further Info :

Pubmed ID

31909868

DOI: Digital Object Identifier

PMC7317912

Related Literature

Article Analysis
・Effective treatment of psoriatic arthritis
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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