Paper Details 
Original Abstract of the Article :
An earlier study using a rat model system indicated that the active ingredients contained in the anti-hypertensive medication amlodipine (AMD) appeared to induce various bowel problems, including constipation and inflammation. A probiotic blend was found to alleviate intestinal complications caused ...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7019348/

データ提供:米国国立医学図書館(NLM)

Amlodipine and the Gut Microbiome: A Shifting Landscape in the Desert of Lipid Metabolism

[Amlodipine (AMD)] is a widely prescribed medication for [high blood pressure]. However, it can sometimes lead to [gastrointestinal side effects]. This study investigates the [relationship between AMD-induced gastrointestinal side effects and changes in the serum lipid metabolome]. The authors used a [rat model] to examine the effects of AMD on [lipid metabolism] and found that [AMD significantly altered the serum lipid profile]. This suggests that [AMD may induce changes in the gut microbiome] that contribute to [gastrointestinal complications].

AMD and the Gut Microbiome: A Symbiotic Relationship in the Desert of Lipid Metabolism

The study's findings suggest that [AMD may disrupt the delicate balance of the gut microbiome], leading to [changes in lipid metabolism] and [gastrointestinal side effects]. The authors emphasize the importance of [understanding the microbiome's role in health] and [exploring potential interventions] to mitigate these complications.

Navigating the Desert: Amlodipine, the Gut Microbiome, and Lipid Metabolism

The study highlights the importance of [considering the gut microbiome] in [managing medication-related side effects]. The authors emphasize the potential of [probiotics] to [alleviate gastrointestinal complications] associated with AMD. In the desert of lipid metabolism, we must be mindful of the interconnectedness of different systems and seek out ways to maintain a healthy balance.

Dr. Camel's Conclusion

The desert of lipid metabolism is a vast and intricate landscape. This study reveals how AMD, a medication commonly used to manage high blood pressure, can disrupt the delicate balance of the gut microbiome. Understanding this interaction is crucial for mitigating gastrointestinal side effects and promoting overall health. Remember, like a camel adapting to the desert's harsh conditions, we must be flexible and resourceful in our approach to managing medication-related side effects.

Date :
  1. Date Completed 2020-10-23
  2. Date Revised 2020-10-23
Further Info :

Pubmed ID

31941114

DOI: Digital Object Identifier

PMC7019348

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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