The efficacy and safety of mirabegron on overactive bladder induced by benign prostatic hyperplasia in men receiving tamsulosin therapy: A systematic review and meta-analysis.

Author: ChenZhipeng, GaoYuan, LiangLiqin, LinJinlei, LiuLudong, SuShunye

Paper Details 
Original Abstract of the Article :
BACKGROUND: We conducted a meta-analysis to assess the efficacy and safety of mirabegron on overactive bladder (OAB) induced by benign prostatic hyperplasia (BPH) in men receiving tamsulosin therapy. METHODS: We performed the analysis by using the Preferred Reporting Items for Systematic Reviews an...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7004736/

データ提供:米国国立医学図書館(NLM)

Mirabegron for Overactive Bladder in Men with Benign Prostatic Hyperplasia

This research dives deep into the world of men's health, specifically focusing on the effectiveness and safety of mirabegron in treating overactive bladder (OAB) in men with benign prostatic hyperplasia (BPH) who are already taking tamsulosin. Like a camel traversing a vast desert, this study systematically reviewed and meta-analyzed existing data to paint a comprehensive picture of mirabegron's impact. The researchers used a rigorous approach, meticulously combing through multiple databases for relevant randomized controlled trials. Their analysis revealed that mirabegron, like a refreshing oasis in the desert, significantly improved OAB symptoms in these men. Key benefits included a decrease in the number of daily urination episodes, urgency episodes, and overall OAB symptom scores. Moreover, mirabegron was found to be generally well-tolerated, with few adverse events. However, the study also cautioned that mirabegron may increase the risk of post-void residual urine volume, a factor that should be closely monitored.

Mirabegron's Effectiveness in Treating OAB

The findings of this study suggest that mirabegron can be a valuable tool in managing OAB symptoms in men with BPH. The researchers found a statistically significant improvement in various OAB-related parameters, with an average decrease of 0.27 micturitions per day, 0.50 urgency episodes per day, and 0.69 points on the total OAB symptom score.

Implications for Men's Health

This research sheds light on a potential therapeutic approach for men struggling with OAB, offering a potential solution that can improve their quality of life. However, it's crucial to remember that mirabegron, like any medication, might have side effects. It's essential to consult a healthcare professional to determine if mirabegron is the right treatment option for you and to discuss potential risks and benefits. While mirabegron seems to be a promising option, close monitoring for post-void residual urine volume is essential.

Dr. Camel's Conclusion

This study sheds light on mirabegron's potential as a treatment for OAB in men with BPH. It's like a camel finding a hidden spring in the desert, offering relief from a persistent ailment. While promising, it's important to remember that every individual is unique, and careful consideration should be given to the potential risks and benefits of any medication. A consultation with a medical professional can help you navigate this complex landscape and make informed decisions about your health.

Date :
  1. Date Completed 2020-01-31
  2. Date Revised 2022-10-05
Further Info :

Pubmed ID

31977871

DOI: Digital Object Identifier

PMC7004736

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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