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Isolated nail lichen planus: An expert consensus on treatment of the classical form.
Author: BaranRobert, DanielC Ralph, Di ChiacchioNilton, GoettmannSophie, GroverChander, HanekeEckart, IorizzoMatilde, LipnerShari R, PiracciniBianca Maria, RichPhoebe, RichertBertrand, RigopoulosDimitris, RubinAdam I, StaraceMichela, TostiAntonella, ZaiacMartin
Original Abstract of the Article :
Lichen planus is a benign inflammatory disorder of unknown etiology that may affect the skin, mucosae, scalp, and nails. When the nails are affected, it may lead to permanent destruction with severe functional and psychosocial consequences. Therefore, prompt diagnosis and early treatment are essenti...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1016/j.jaad.2020.02.056
データ提供:米国国立医学図書館(NLM)
Addressing the Challenge of Nail Lichen Planus: A Consensus on Treatment
Lichen planus, a condition that can feel like a persistent desert wind, affects the skin, mucous membranes, scalp, and nails, causing discomfort and potential for permanent damage. This study focuses on the impact of lichen planus on nails, a particularly challenging area, as it can lead to significant functional and psychosocial consequences. This research, much like a group of desert nomads sharing their expertise, brings together a panel of experts to develop consensus-based recommendations for managing this condition.
The experts, like seasoned travelers navigating the desert, recognize the importance of early diagnosis and treatment to prevent further complications. However, the path to effective treatment is not straightforward. Current literature on nail lichen planus is limited, and there are no established guidelines, similar to navigating an uncharted desert. This study, therefore, serves as a valuable guide for clinicians, providing practical recommendations specifically for the classical form of nail lichen planus, when it affects primarily the nails.
Topical Treatments: A Limited Oasis
The experts caution that topical treatments, while seemingly straightforward, offer limited short-term benefits and may even lead to long-term side effects. This is similar to finding a temporary oasis that might not sustain a traveler on a long journey. Instead, they recommend intralesional and intramuscular triamcinolone acetonide as first-line therapies, like discovering a more permanent and reliable oasis.
Oral Retinoids and Immunosuppressive Agents: Alternate Paths in the Desert
The study also explores alternative treatment options, similar to finding different paths through the desert. Oral retinoids are suggested as second-line choices, and immunosuppressive agents, like finding a hidden oasis, might also be considered. However, the experts emphasize the need for careful consideration and close monitoring when using these therapies, recognizing that each approach has its own set of challenges and risks, like the potential for unexpected hazards in the desert.
Dr.Camel's Conclusion
The challenge of treating nail lichen planus is like navigating a vast and often unforgiving desert. This study, like a group of experienced desert guides, offers valuable insights and practical recommendations, guiding clinicians toward more effective treatment strategies for this challenging condition. However, the journey is far from over, and further research is needed to identify even more reliable and sustainable oases, ultimately ensuring a better outcome for those affected by this condition.
Date :
- Date Completed 2021-04-23
- Date Revised 2021-04-23
Further Info :
Related Literature
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