Paper Details 
Original Abstract of the Article :
The aim of this study is to develop, characterize and compare conventional liposome, deformable liposome (transfersome) and microemulsion formulations as potential topical delivery systems for meloxicam. Liposomes were characterized in terms of vesicle size, zeta potential and entrapment efficiency....See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7151031/

データ提供:米国国立医学図書館(NLM)

Topical Delivery of Meloxicam: A Camel's Perspective on Topical NSAID Delivery

The field of drug delivery is like a vast desert, constantly seeking new oases of efficiency and effectiveness. This research delves into the intriguing world of topical delivery systems, specifically focusing on meloxicam, a non-steroidal anti-inflammatory drug (NSAID). The researchers set out to explore the potential of liposomes and microemulsions as vehicles for delivering meloxicam to the skin. They meticulously characterized these systems, comparing their size, charge, and ability to encapsulate the drug. Through an ex vivo skin permeation study, they compared the delivery profiles of these formulations. Their findings suggest that topical delivery of meloxicam using these systems could offer a promising alternative to conventional oral NSAID delivery, potentially enhancing both local and systemic effects while minimizing unwanted side effects.

Liposomes and Microemulsions: A New Oasis for Meloxicam Delivery

This research provides evidence that topical delivery systems like liposomes and microemulsions can significantly improve the delivery of meloxicam to the skin. The study found that these formulations exhibited better permeation than conventional methods, suggesting a more efficient and targeted delivery of the drug to the desired site of action.

A Camel's Insight: Skin Deep Benefits

This research offers a glimpse into the exciting future of topical drug delivery. Imagine a world where skin conditions like arthritis or inflammation are effectively managed through the simple application of a cream or gel. This could lead to a reduction in oral NSAID use, potentially mitigating the risk of gastrointestinal complications associated with these drugs. However, it's crucial to remember that topical delivery is not always the answer. The effectiveness of these systems depends on various factors, including the specific drug and the condition being treated. Further research is needed to fully understand the potential and limitations of topical delivery systems for different medications.

Dr.Camel's Conclusion

This study highlights the promise of liposomes and microemulsions as topical delivery systems for meloxicam, suggesting a potential shift towards more localized and targeted treatment approaches. As a camel who has traversed vast deserts, I see a future where topical delivery becomes a more common and effective way to manage various conditions.

Date :
  1. Date Completed n.d.
  2. Date Revised 2020-09-28
Further Info :

Pubmed ID

32245190

DOI: Digital Object Identifier

PMC7151031

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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