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Health and economic outcomes of treatment with extended-release naltrexone among pre-release prisoners with opioid use disorder (HOPPER): protocol for an evaluation of two randomized effectiveness trials.

Author: GordonMichael S, JalaliAli, JengPhilip J, MurphySean M, PolskyDaniel, PooleSabrina A, VocciFrank J, WoodyGeorge E

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, N.I.H., ExtramuralResearch funding provided by the NIH to external research institutions and researchers.

Overview

Extended-release naltrexone (XR-NTX) is the most widely accepted, evidence-based pharmacotherapy for opioid use disorder (OUD) in correctional settings, but its high cost is a barrier to its use.
Paper Details　
Original Abstract of the Article :
Persons with an opioid use disorder (OUD) who were incarcerated face many challenges to remaining abstinent; concomitantly, opioid-overdose is the leading cause of death among this population, with the initial weeks following release proving especially fatal. Extended-release naltrexone (XR-NTX) is ...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7178627/

データ提供：米国国立医学図書館（NLM）

Extended-Release Naltrexone for Opioid Use Disorder: A Protocol for Evaluating Health and Economic Outcomes

This research protocol outlines two randomized effectiveness trials evaluating the health and economic outcomes of extended-release naltrexone (XR-NTX) treatment for opioid use disorder (OUD) among pre-release prisoners. The study aims to assess the effectiveness of XR-NTX in reducing opioid overdose rates, improving health outcomes, and evaluating the economic implications of this treatment approach. The study recognizes the importance of addressing the unique challenges faced by individuals with OUD who are incarcerated, highlighting the potential for XR-NTX to improve both individual and societal well-being.

Addressing Opioid Use Disorder in Incarcerated Populations

This research protocol underscores the critical need to address opioid use disorder (OUD) in incarcerated populations. The study aims to evaluate the effectiveness of extended-release naltrexone (XR-NTX) in reducing overdose rates, improving health outcomes, and assessing the economic implications of this treatment approach. The study recognizes the high risk of overdose among individuals with OUD who are incarcerated, emphasizing the potential for XR-NTX to significantly improve both individual and societal well-being.

Effective Treatment Strategies for Opioid Use Disorder

This research protocol highlights the importance of developing effective treatment strategies for opioid use disorder (OUD). The study aims to evaluate the effectiveness of extended-release naltrexone (XR-NTX) in reducing overdose rates and improving health outcomes. Just as a camel adapts to its desert environment, addressing the complex challenges of OUD requires a comprehensive and informed approach. This research is a testament to the ongoing efforts to develop effective treatment strategies for this challenging condition.

Dr.Camel's Conclusion

This research protocol outlines a crucial step forward in addressing the challenges of opioid use disorder (OUD) in incarcerated populations. The study's focus on evaluating the health and economic outcomes of extended-release naltrexone (XR-NTX) treatment is a testament to the ongoing efforts to develop effective and compassionate strategies for managing this complex condition. As a wise old camel who has witnessed the resilience of life in the harshest environments, I believe that finding solutions to complex problems requires a combination of compassion, innovation, and a commitment to improving well-being.

Date :
  1. Date Completed 2021-09-01
  2. Date Revised 2021-09-01
Further Info :

Pubmed ID

32321570

DOI: Digital Object Identifier

PMC7178627

Related Literature

Article Analysis
・Effective treatment of opioid use
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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