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Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne.

Author: LiuGuan J, LiuHaibo, LiuLing, PeinemannFrank, SangHong, XiaJun, YuHaiyan

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

A review of 49 trials on topical acne treatments found that azelaic acid is probably less effective than benzoyl peroxide for treatment response but probably makes little or no difference when compared to tretinoin. For other topical treatments and outcomes, the quality of evidence was low or very low.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Acne is an inflammatory disorder with a high global burden. It is common in adolescents and primarily affects sebaceous gland-rich areas. The clinical benefit of the topical acne treatments azelaic acid, salicylic acid, nicotinamide, sulphur, zinc, and alpha-hydroxy acid is unclear. OBJ...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7193765/

データ提供：米国国立医学図書館（NLM）

Treating Acne: A Comprehensive Overview of Topical Treatments

This study delves into the common skin condition of acne, exploring the effectiveness of various topical treatments. The research systematically reviews and compares the efficacy of different agents, including azelaic acid, salicylic acid, nicotinamide, sulfur, zinc, and alpha-hydroxy acid, in treating acne.

Navigating the Treatment Landscape: A Comparative Analysis of Topical Agents

The meta-analysis, based on data from multiple clinical trials, provides a comprehensive overview of the evidence for the effectiveness of various topical acne treatments. The study revealed that some treatments, such as azelaic acid and salicylic acid, may be effective for acne, but the quality of evidence supporting their use is often limited.

A Personalized Approach: Tailoring Treatment to Individual Needs

This research highlights the importance of a personalized approach to acne treatment, considering the individual patient's specific needs and the potential side effects associated with different therapies. The study underscores the need for more robust clinical trials to clarify the effectiveness and safety of various topical acne treatments.

Dr.Camel's Conclusion

Imagine a desert where the sands of acne flare up, creating a landscape of blemishes and discomfort. This study, like a desert oasis offering a variety of remedies, explores the effectiveness of different topical treatments for acne. The research highlights the importance of a comprehensive approach, considering individual needs and seeking guidance from healthcare professionals to navigate the path towards clear and healthy skin.

Date :
  1. Date Completed 2020-09-11
  2. Date Revised 2022-09-15
Further Info :

Pubmed ID

32356369

DOI: Digital Object Identifier

PMC7193765

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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