Efficacy and safety of ceritinib in anaplastic lymphoma kinase-rearranged non-small cell lung cancer: A systematic review and meta-analysis.

Author: DengXiao-Hui, GeXiao-Zhu, TianWei, YuanYuan, YueRui, ZhangPing

Paper Details 
Original Abstract of the Article :
Ceritinib is a new, oral, potent and selective second-generation anaplastic lymphoma kinase (ALK) inhibitor approved by the Food and Drug Administration of the United States in April 2014. It is active in crizotinib-resistant patients, especially in patients with non-small cell lung cancer (NSCLC) a...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7384129/

データ提供:米国国立医学図書館(NLM)

Ceritinib: A New Oasis for ALK-Rearranged NSCLC

Anaplastic lymphoma kinase (ALK)-rearranged non-small cell lung cancer (NSCLC) is a challenging form of cancer, like a formidable desert sandstorm. This research, like a team of scientists searching for a cure, explores the efficacy and safety of ceritinib, a new oral ALK inhibitor, in patients with ALK-rearranged NSCLC. The researchers conducted a systematic review and meta-analysis, gathering data from multiple studies to evaluate the effectiveness of ceritinib. The results, like a shimmering oasis in the desert of lung cancer, revealed that ceritinib, particularly for crizotinib-resistant patients, showed significant clinical benefits, including improved tumor response and prolonged survival.

Ceritinib: A Powerful Weapon in the Fight Against Lung Cancer

This research, like a well-trained caravan leader navigating a challenging terrain, highlights the potential of ceritinib as a valuable weapon in the fight against ALK-rearranged NSCLC. This drug, like a hidden spring in the desert, offers hope and improved outcomes for patients, particularly those who have not responded to other treatments.

A New Era of Lung Cancer Treatment

The development of targeted therapies like ceritinib, like a new oasis blooming in the desert of lung cancer research, marks a significant advancement in the treatment of ALK-rearranged NSCLC. This research provides valuable insights for clinicians and patients, paving the way for a brighter future in the fight against this devastating disease.

Dr.Camel's Conclusion

Ceritinib, like a refreshing breeze in the desert of lung cancer, offers a new wave of hope for patients with ALK-rearranged NSCLC. This targeted therapy, like a hidden spring in the desert, provides a crucial source of relief and improved outcomes, enhancing the lives of those facing this challenging diagnosis.

Date :
  1. Date Completed 2021-02-08
  2. Date Revised 2021-02-08
Further Info :

Pubmed ID

32369239

DOI: Digital Object Identifier

PMC7384129

SNS
PICO Info
in preparation
Languages

English

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