Efficacy of Tamsulosin plus Tadalafil versus Tamsulosin as Medical Expulsive Therapy for Lower Ureteric Stones: A Randomized Controlled Trial.

Author: ChalisePawan Raj, ChapagainSuman, ChudalSampanna, GnyawaliDiwas, GyawaliPrem Raj, LuitelBhoj Raj, ParajuliPurushottam, PoudyalSujeet, PradhanManish Man, SharmaUttam, SigdelPrem Raj

Paper Details 
Original Abstract of the Article :
Label="INTRODUCTION" NlmCategory="BACKGROUND">Urolithiasis is one of the common disorder with which about 1/5<sup>th</sup> is found in the ureter, of which 2/3<sup>rd</sup> is seen in the lower ureter. Medical expulsive therapy is one of the routine modalities of treatment which uses various drugs a...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7204220/

データ提供:米国国立医学図書館(NLM)

Medical Expulsive Therapy for Lower Ureteric Stones: A Quest for Effective Treatment

Urolithiasis, the formation of kidney stones, is a common and often painful condition. Lower ureteric stones, stones located in the lower part of the ureter, can be particularly challenging to treat. Medical expulsive therapy, a non-surgical approach using medications to help pass the stone, is often employed. This study, published in the journal [Journal Name], investigates the effectiveness of different drug combinations for medical expulsive therapy in lower ureteric stones.

The researchers conducted a randomized controlled trial to compare the efficacy of combining tamsulosin, an alpha-blocker, with tadalafil, a phosphodiesterase type 5 inhibitor, versus tamsulosin alone as medical expulsive therapy for lower ureteric stones. This study aimed to determine if the combination therapy offered any advantages over the single-drug approach.

The study's findings, like a guide through a treacherous desert, suggest that combining tamsulosin with tadalafil may be more effective than using tamsulosin alone in facilitating stone expulsion. This finding provides valuable information for urologists treating patients with lower ureteric stones, offering a potential path toward more successful treatment.

Medical Expulsive Therapy: A Pathway to Stone Passage

The study's results suggest that combination therapy, combining tamsulosin with tadalafil, can potentially improve the success rate of medical expulsive therapy for lower ureteric stones. This finding could benefit patients by increasing the likelihood of successful stone passage and minimizing the need for more invasive procedures.

Navigating the Desert of Kidney Stones: A Guide for Patients

If you are diagnosed with a kidney stone, it's essential to consult with a urologist to discuss the most appropriate treatment options. This study provides valuable insights into the effectiveness of different medical expulsive therapy approaches, empowering you to make informed decisions about your care.

Dr.Camel's Conclusion

This study offers a compelling case for combining tamsulosin with tadalafil as medical expulsive therapy for lower ureteric stones. The research suggests that this combination may lead to higher success rates in stone expulsion, potentially benefiting patients by minimizing the need for more invasive interventions.

Date :
  1. Date Completed n.d.
  2. Date Revised 2022-04-14
Further Info :

Pubmed ID

32411212

DOI: Digital Object Identifier

PMC7204220

Related Literature

SNS
PICO Info
in preparation
Languages

English

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