Paper Details 
Original Abstract of the Article :
The aim of this study was to formulate an easily-administered, safe and effective dosage form loaded with meclizine for treatment of chemotherapy-induced nausea and vomiting (CINV) through the buccal route. CINV comprises bothersome side effects accompanying cytotoxic drugs administration in cancer ...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://doi.org/10.1016/j.ijpharm.2020.119411

データ提供:米国国立医学図書館(NLM)

A New Oasis in the Desert of Chemotherapy Side Effects

This study explores the world of [pharmacology and cancer treatment], investigating a new approach to reducing the debilitating side effects of chemotherapy, specifically nausea and vomiting. The researchers developed a buccal film containing meclizine hydrochloride, a drug known to reduce nausea and vomiting, loaded into nanoparticles made of chitosan and pectin. They found that this new formulation was effective at reducing chemotherapy-induced nausea and vomiting in animal models, with a significant improvement in symptoms compared to free meclizine.

A Buccal Film Solution: Easing the Burden of Chemotherapy

The study shows that this new buccal film formulation containing meclizine hydrochloride was effective at reducing chemotherapy-induced nausea and vomiting in animal models. It's like finding a refreshing oasis in the desert of chemotherapy side effects, offering relief and comfort to patients undergoing treatment.

Hope for Cancer Patients: A Smoother Journey Through the Desert of Treatment

This research offers hope for cancer patients struggling with chemotherapy-induced nausea and vomiting, suggesting that this new buccal film formulation could be a valuable tool for improving their quality of life during treatment. It's a reminder that with continued research and development, we can find better ways to manage the challenges of cancer treatment.

Dr.Camel's Conclusion

This study is a testament to the ingenuity and creativity of scientists in the field of cancer treatment. It highlights the potential of innovative drug delivery systems to improve the quality of life for patients undergoing chemotherapy.

Date :
  1. Date Completed 2021-03-03
  2. Date Revised 2021-03-03
Further Info :

Pubmed ID

32423876

DOI: Digital Object Identifier

10.1016/j.ijpharm.2020.119411

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.