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Paper Details

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Paper Details

Dose-response study of prazosin in Raynaud's phenomenon: clinical effectiveness versus side effects.

Author: ThienT, WollersheimH

Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.

Controlled Clinical TrialA clinical trial that evaluates the effectiveness of a treatment by comparing a group that receives the intervention with a group that receives a placebo or standard treatment.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Prazosin, a medication for Raynaud's phenomenon, was effective at 3 mg daily. Higher doses did not show a significant increase in effectiveness but had a higher incidence of side effects, particularly orthostatic hypotension.

Paper Details　

Original Abstract of the Article :

In a dose-response study of prazosin in 24 patients with Raynaud's phenomenon, the clinical effectiveness and side effects of 3, 6, and 12 mg prazosin administered daily were compared. Diary analysis and measurement of finger skin blood flow and temperature before, during, and after cold challenge s...See full text at original site

Dr.Camel's Paper Summary Blog

in preparation

Date :

Date Completed 1989-06-02
Date Revised 2019-08-24

Further Info :

Pubmed ID

DOI: Digital Object Identifier

10.1002/j.1552-4604.1988.tb05720.x

Related Literature

Article Analysis

・Side Effects of prazosin

SNS

PICO Info

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Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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