Long-term changes in the gut microbiota after 14-day bismuth quadruple therapy in penicillin-allergic children.

Author: HuangYing, LuJunping, LuXiaolan, MiaoShijian, SunHua, WangYuhuan, WuJie, YeZiqing, ZhouYing

Paper Details 
Original Abstract of the Article :
BACKGROUND: Penicillin-allergic children who are infected with Helicobacter pylori constitute a relatively common subgroup. We aimed to study the short-term and long-term effects of bismuth quadruple therapy on gut microbiota in penicillin-allergic children. METHODS: We prospectively recruited trea...See full text at original site
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引用元:
https://doi.org/10.1111/hel.12721

データ提供:米国国立医学図書館(NLM)

H. pylori Treatment and the Gut Microbiota: A delicate Ecosystem

The gut microbiota, a complex ecosystem of trillions of microorganisms, plays a crucial role in human health, and this research explores the impact of bismuth quadruple therapy on the gut microbiota in penicillin-allergic children infected with *Helicobacter pylori*. The authors, like meticulous ecologists studying a sensitive ecosystem, conducted a prospective study to investigate the short-term and long-term effects of this therapy on the gut microbiota. Their findings, like a detailed map of a microbial landscape, reveal that bismuth quadruple therapy causes short-term dysbiosis, with most changes recovering within a year, suggesting the long-term safety of this treatment for *H. pylori* eradication.

Restoring Balance: The Gut Microbiota's Resilience

This study, like a team of environmental engineers restoring a damaged ecosystem, demonstrates the resilience of the gut microbiota. The findings suggest that while bismuth quadruple therapy can cause short-term dysbiosis, the gut microbiota can generally recover within a year, highlighting its remarkable ability to adapt and maintain a healthy balance. This research, like a beacon of hope in the desert, assures us that appropriate interventions, like *H. pylori* eradication, can ultimately lead to a restoration of gut microbiome health.

The Importance of Gut Health: A Journey of Understanding

This research, like a guidebook to the intricate world of the gut microbiota, highlights the importance of understanding and maintaining gut health. The study's findings underscore the need for targeted therapies that minimize disruptions to the gut microbiome while effectively addressing specific health concerns. This research, like a well-maintained caravan route, guides us towards a better understanding of the interconnectedness of gut health and overall well-being, emphasizing the crucial role of the gut microbiota in maintaining health and resilience.

Dr.Camel's Conclusion

This research journey, like a trek across a vast and diverse desert, highlights the delicate balance within the gut microbiota and the importance of maintaining its health. The study's findings provide valuable insights into the impact of bismuth quadruple therapy on the gut microbiome, emphasizing the need for targeted therapies that minimize disruptions while effectively addressing specific health concerns.

Date :
  1. Date Completed 2021-07-02
  2. Date Revised 2021-07-02
Further Info :

Pubmed ID

32656891

DOI: Digital Object Identifier

10.1111/hel.12721

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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