Paper Details

  1. Home
  2. Paper Details

Dosage and time effects of inhaled budesonide on bronchial hyperreactivity.

Author: BoorsmaM, De VriesK, KoëterG H, KraanJ, KuklerJ, SluiterH J, van der MarkT W

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Inhaled budesonide was effective in reducing bronchial hyperreactivity in allergic asthmatic patients. The effect was dose-dependent, with a higher dose (800 micrograms/day) producing a larger change in methacholine provocation concentrations than a lower dose (200 micrograms/day).
Paper Details　
Original Abstract of the Article :
In a double-blind study of 2 parallel groups of 15 allergic asthmatic patients each, we investigated whether treatment with inhaled budesonide has a dose- and time-dependent effect on the degree of bronchial hyperreactivity. The patients were randomly allocated to treatment with either 200 or 800 mi...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1164/ajrccm/137.1.44

データ提供：米国国立医学図書館（NLM）

Budesonide: A Dose-Dependent Impact on Asthma

Asthma is a chronic respiratory condition that affects millions worldwide. This study delves into the effectiveness of inhaled budesonide, a common medication for asthma, and investigates its dose-dependent effects on bronchial hyperreactivity, a key characteristic of asthma. The researchers conducted a double-blind study with two groups of allergic asthmatic patients, comparing the effects of different doses of budesonide.

Higher Dose, Higher Impact

The results revealed a clear dose-dependent effect of budesonide. Patients receiving a higher dose (800 micrograms per day) showed a significantly greater improvement in bronchial hyperreactivity compared to those receiving a lower dose (200 micrograms per day). This suggests that increasing the dose of budesonide might be beneficial for some patients with asthma, particularly those with more severe or persistent symptoms.

A Clearer Path for Asthma Control

This study offers valuable insights into the optimal dosing of budesonide for asthma management. It's a reminder that every patient is unique and their individual needs should be considered when determining the appropriate dose of medication. This research helps pave the way for more personalized asthma care, potentially leading to better control of symptoms and improved quality of life for patients.

Dr. Camel's Conclusion

This study is like a desert oasis, providing valuable information about the effectiveness of budesonide for asthma. It highlights the importance of considering the dose of medication, a crucial factor in optimizing treatment outcomes. By understanding the dose-dependent effects of budesonide, we can provide more personalized care, helping patients navigate the sometimes challenging landscape of asthma management.

Date :
  1. Date Completed 1988-02-10
  2. Date Revised 2015-11-19
Further Info :

Pubmed ID

3276257

DOI: Digital Object Identifier

10.1164/ajrccm/137.1.44

Related Literature

Article Analysis
・Effects of budesonide
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.