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Characteristics Associated With Treatment Failure 1 Year After Midurethral Sling in Women With Mixed Urinary Incontinence.

Author: , Borello-FranceDiane, CarperBenjamin, DunivanGena, GantzMarie G, MazloomdoostDonna, MoalliPamela, NewmanDiane K, NguyenJohn N, RichterHolly E, RidgewayBeri, SmithAriana L, SungVivian W, WeidnerAlison C

Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, N.I.H., ExtramuralResearch funding provided by the NIH to external research institutions and researchers.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Retracted PublicationCases where a publication has been formally withdrawn due to the discovery of serious errors or misconduct.

Overview

This study examined factors associated with treatment failure 1 year after midurethral sling surgery for mixed urinary incontinence. Analysis of data from 403 women who participated in a randomized trial found that previous overactive bladder medication use, detrusor overactivity on cystometrogram, body mass index, and Valsalva leak point pressure less than 60 cm H2O were associated with overall treatment failure. Women with more severe urgency symptoms at baseline may benefit from combining behavioral and pelvic floor muscle therapy with midurethral sling.
Paper Details　
Original Abstract of the Article :
OBJECTIVE: To evaluate characteristics associated with treatment failure 1 year after midurethral sling in women with mixed urinary incontinence. METHODS: Four hundred three women who participated in a randomized trial that compared midurethral sling and behavioral and pelvic floor muscle therapy (...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/32769647

データ提供：米国国立医学図書館（NLM）

Identifying Risk Factors for Treatment Failure After Midurethral Sling for Mixed Urinary Incontinence

This study delves into the world of [midurethral sling], a surgical procedure commonly used to treat [mixed urinary incontinence]. The researchers investigated factors associated with [treatment failure] one year after midurethral sling surgery in women with mixed urinary incontinence, identifying potential predictors of success or failure in this complex surgical intervention.

Predictors of Treatment Failure

The study identified several factors associated with treatment failure after midurethral sling surgery, including: [previous overactive bladder medication use], [detrusor overactivity on cystometrogram], [body mass index], and [Valsalva leak point pressure less than 60 cm H2O]. These findings suggest that women with these characteristics may be at higher risk for treatment failure after midurethral sling surgery and may benefit from alternative or additional treatment strategies.

Tailoring Treatment Strategies for Optimal Outcomes

This study provides valuable information for healthcare professionals who treat women with mixed urinary incontinence. Understanding the factors associated with treatment failure can help guide treatment decisions, personalize care, and improve outcomes. The findings suggest that women with more severe urgency symptoms at baseline may benefit from combining midurethral sling with [perioperative behavioral and pelvic floor muscle therapy].

Dr.Camel's Conclusion

This study highlights the importance of a comprehensive and personalized approach to managing mixed urinary incontinence. It's like navigating a desert – we need to understand the unique challenges and complexities of each case to find the most effective path to treatment. This research underscores the need for careful patient selection, individualized treatment strategies, and ongoing monitoring to optimize outcomes for women with mixed urinary incontinence.

Date :
  1. Date Completed 2020-11-25
  2. Date Revised 2022-10-19
Further Info :

Pubmed ID

32769647

DOI: Digital Object Identifier

00006250-202009000-00007

Related Literature

Article Analysis
・Effective treatment of urinary incontinence
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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