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Active monitoring, radical prostatectomy and radical radiotherapy in PSA-detected clinically localised prostate cancer: the ProtecT three-arm RCT.

Author: BlazebyJane, BollinaPrasad, BryantRichard, CattoJames, DavisMichael, DobleAndrew, DohertyAlan, DonovanJenny L, GarfieldKirsty, GillattDavid, GnanapragasamVincent, HamdyFreddie C, HoldingPeter, HughesOwen, KockelberghRoger, KynastonHoward, LaneJ Athene, MartinRichard M, MasonMalcolm, MetcalfeChris, NealDavid, NobleSian, OxleyJon, PaezEdgar, PaulAlan, PetersTim J, PowellPhilip, PrescottStephen, RobinsonMary, RosarioDerek, RoweEdward, StaffurthJohn, TurnerEmma L, WadeJulia, WalshEleanor, YoungGrace

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Prostate cancer is a common cancer in the UK. Current screening and treatment practices often lead to either unnecessary treatment or missed opportunities for effective treatment. The study highlights the need for more research, particularly randomized controlled trials, to compare different treatment approaches for prostate cancer.
Paper Details　
Original Abstract of the Article :
Prostate cancer is the most common cancer among men in the UK. Prostate-specific antigen testing followed by biopsy leads to overdetection, overtreatment as well as undertreatment of the disease. Evidence of treatment effectiveness has lacked because of the paucity of randomised controlled trials co...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7443739/

データ提供：米国国立医学図書館（NLM）

Active Monitoring, Radical Prostatectomy and Radical Radiotherapy in PSA-Detected Clinically Localised Prostate Cancer

Prostate cancer is a common ailment, much like a persistent sandstorm that plagues men. The challenge lies in finding the right approach for managing this disease, as overtreatment can lead to unnecessary complications, while undertreatment could leave the cancer unchecked. This study, conducted in the UK, aims to provide a clearer picture by comparing three different treatment strategies for prostate cancer.

A Search for the Optimal Treatment Strategy

The study was a randomized controlled trial, which means it was designed to provide robust evidence by comparing different treatment approaches. The researchers studied three arms: active monitoring, radical prostatectomy, and radical radiotherapy. Active monitoring involves close observation without immediate treatment, while the other two options involve surgical or radiation-based interventions. This study aims to contribute valuable insights into the best approach for treating prostate cancer, allowing us to better navigate the complex landscape of this disease.

Navigating the Sands of Prostate Cancer Treatment

This research is important because it investigates the effectiveness of different treatment options for prostate cancer, helping physicians make informed decisions. Finding the right balance between effective treatment and minimizing side effects is like navigating a tricky desert terrain. This study provides valuable data to guide us in our journey towards better patient care.

Dr.Camel's Conclusion

This study provides a valuable roadmap for navigating the complex terrain of prostate cancer treatment. By comparing different treatment strategies, we can gain a better understanding of which approach is most effective in different situations. This knowledge is crucial for providing personalized care to patients and maximizing their chances of a positive outcome.

Date :
  1. Date Completed 2021-09-16
  2. Date Revised 2021-09-16
Further Info :

Pubmed ID

32773013

DOI: Digital Object Identifier

PMC7443739

Related Literature

Article Analysis
・Effective treatment of prostate cancer
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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