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Blinded comparison of cefuroxime to cefaclor for lower respiratory tract infections.

Author: AnthonyW C, CraigW, FileT M, LiflandP, SchleupnerC J, TanJ, VogelmanB

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Cefuroxime axetil was at least as effective as cefaclor for treating lower respiratory tract infections. Cefuroxime axetil, administered every 12 hours, had a bacteriologic cure rate of 86% compared to 60% for cefaclor.
Paper Details　
Original Abstract of the Article :
Cefuroxime axetil was compared with cefaclor for the therapy for lower respiratory tract infections. Sixty-one patients were randomized to receive the following drug dosages: (1) cefuroxime axetil, 250 mg orally every 12 hours (21 patients); (2) cefuroxime axetil, 500 mg orally every 12 hours (21 pa...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/3277562

データ提供：米国国立医学図書館（NLM）

Cefuroxime vs. Cefaclor: A Head-to-Head Comparison for Respiratory Infections

Lower respiratory tract infections, like bronchitis and pneumonia, are common ailments. This study compares the effectiveness of two antibiotics, cefuroxime axetil and cefaclor, in treating these infections. The researchers conducted a randomized controlled trial, assigning patients to receive either cefuroxime or cefaclor and then assessing clinical and bacteriologic outcomes.

Cefuroxime: A Strong Contender for Respiratory Infections

The study found that cefuroxime, given twice a day, was at least as effective as cefaclor in treating lower respiratory tract infections. Cefuroxime also demonstrated a higher rate of bacteriologic cure, indicating its effectiveness in eliminating the bacteria causing the infection.

Health Implications and Everyday Applications

This study provides valuable information for healthcare providers when choosing antibiotics for lower respiratory tract infections. The findings suggest that cefuroxime can be a reliable treatment option, potentially offering advantages over older antibiotic agents.

Dr.Camel's Conclusion

The desert of respiratory infections can be a challenging place to navigate. This study helps us choose the right weapon to combat those infections. Cefuroxime is like a trusty camel, strong and capable of navigating the toughest terrains. It's a valuable tool in the fight against lower respiratory tract infections, providing hope for a quicker and more effective recovery.

Date :
  1. Date Completed 1988-03-08
  2. Date Revised 2016-11-23
Further Info :

Pubmed ID

3277562

DOI: Digital Object Identifier

3277562

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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