Paper Details
- Home
- Paper Details
Pharmacologic effects of oseltamivir in immunocompromised adult patients as assessed by population PK/PD analysis and drug-disease modelling for dosing regimen optimization.
Author: BhardwajRajinder, DangSteve, GibianskyLeonid, Lemenuel-DiotAnnabelle, Nasmyth-MillerClare, PatelKashyap, RavvaPatanjali, SmithPatrick F, SturmStefan, ZwanzigerElke
Original Abstract of the Article :
AIM: Pharmacologic effects were analysed to determine a dose recommendation for oseltamivir in immunocompromised (IC) adults with influenza. METHODS: Quantitative clinical pharmacology methods were applied to data from 160 adult IC patients (aged 18-78 years) from two studies (NV20234, 150 patients...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8246794/
データ提供:米国国立医学図書館(NLM)
Optimizing Oseltamivir Dosing for Immunocompromised Patients
Influenza, that pesky virus that can leave you feeling like a lost camel in a sandstorm, can be particularly challenging for individuals with weakened immune systems. This study dives into the world of oseltamivir, a medication used to treat influenza, and explores how best to use it for immunocompromised patients. The researchers used a sophisticated mathematical model to analyze data from a large group of patients. They found that oseltamivir works well in immunocompromised patients when administered at the standard dose, but it's important to start treatment early. Their findings, much like a well-placed oasis in the desert, provide a roadmap for optimizing treatment for these vulnerable individuals.
Oseltamivir: A Powerful Tool for Fighting Influenza
This study delivers a clear message: early treatment with oseltamivir can significantly reduce the impact of influenza. The researchers emphasize that starting treatment within 48 hours of symptom onset is crucial, It's like finding a hidden well of water before your camel succumbs to dehydration!
Oseltamivir: A Crucial Weapon in the Fight Against Influenza
This study sheds light on the importance of early intervention and highlights the potential of oseltamivir in managing influenza, especially for those with compromised immune systems. It's a reminder that knowledge and proper treatment are vital in the face of this formidable adversary. This research is a step towards creating a healthier future, where the threat of influenza is less daunting.
Dr.Camel's Conclusion
This study, like a camel traversing a vast desert, has successfully navigated the complex landscape of influenza treatment. The researchers, using a sophisticated mathematical model, have unearthed valuable insights into how to optimize oseltamivir dosing for immunocompromised patients. This research serves as a valuable guide, ensuring that patients with weakened immune systems receive the best possible care when battling influenza.
Date :
- Date Completed 2021-07-26
- Date Revised 2021-07-26
Further Info :
Related Literature
English
This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.