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Memantine, Donepezil, or Combination Therapy-What is the best therapy for Alzheimer's Disease? A Network Meta-Analysis.

Author: GuoJiaxun, HuangYunxia, LiuRuishu, WangZhenyu, ZhangNan, ZhangRuihan

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Alzheimer's disease (AD) is a debilitating brain disorder that affects millions worldwide. Memantine and donepezil are common medications used alone or together to treat AD. This study analyzed research comparing these treatments to a placebo (inactive treatment) to see how well they work in managing AD.
Paper Details　
Original Abstract of the Article :
Alzheimer's disease (AD) is a degenerative brain disease that progresses over time, heavily burdening patients, families, and aging societies worldwide. Memantine and donepezil are frequently used in its treatment, both as monotherapy and in combination. This multiple treatment comparison meta-analy...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7667299/

データ提供：米国国立医学図書館（NLM）

Memantine, Donepezil, or Combination Therapy: Navigating the Treatment Landscape for Alzheimer's Disease

This [network meta-analysis] assesses the comparative effectiveness of different treatment options for [Alzheimer's disease (AD)], focusing on the commonly used medications [memantine], [donepezil], and their combination. The study aims to determine the optimal treatment regimen for [AD] by comparing the efficacy of these medications and [placebo] in managing the symptoms of the disease.

A Comprehensive Comparison of Treatment Options for Alzheimer's Disease

This meta-analysis provides a comprehensive comparison of the efficacy of [memantine], [donepezil], and their combination in managing [Alzheimer's disease (AD)]. The study's findings offer valuable insights for clinicians seeking to optimize treatment strategies for patients with [AD]. The research highlights the importance of considering the individual needs of patients when selecting the most appropriate treatment approach.

Exploring the Treatment Landscape for Alzheimer's Disease

This research emphasizes the ongoing quest for effective treatments for [Alzheimer's disease (AD)], a debilitating condition that affects millions worldwide. Just as a camel navigates the challenging terrain of the desert, researchers are constantly exploring new avenues to combat this devastating disease. This meta-analysis provides a valuable roadmap for understanding the current treatment landscape for [AD] and guiding future research efforts.

Dr.Camel's Conclusion

This comprehensive meta-analysis offers valuable insights into the treatment landscape for [Alzheimer's disease (AD)], providing a framework for clinicians to make informed decisions regarding treatment options. The research highlights the importance of tailoring treatment strategies to individual patient needs and underscores the ongoing need for innovation and further research in the fight against this challenging disease.

Date :
  1. Date Completed 2021-06-24
  2. Date Revised 2021-06-24
Further Info :

Pubmed ID

32914577

DOI: Digital Object Identifier

PMC7667299

Related Literature

Article Analysis
・Effective treatment of alzheimer's disease
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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