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Anti-cytokine targeted therapies for ANCA-associated vasculitis.

Author: BalaMalgorzata M, JarczewskiJarosław D, KopernyMagdalena, Malecka-MassalskaTeresa J, SzczeklikWojciech, ZajacJoanna F

Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

ANCA-associated vasculitis (AAV) is a rare autoimmune disease that affects small blood vessels. It affects about 1 in 10,000 people, with no clear cause. AAV can be treated with medications that target specific inflammatory proteins in the body, which may reduce side effects and improve outcomes.
Paper Details　
Original Abstract of the Article :
Anti-neutrophilic cytoplasmic antibodies (ANCA)-associated vasculitis (AAV) are a group of rare auto-inflammatory diseases that affects mainly small vessels. AAV includes: granulomatosis with polyangiitis (GPA), microscopic polyangiitis (MPA) and eosinophilic granulomatosis with polyangiitis (EGPA)....See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8094990/

データ提供：米国国立医学図書館（NLM）

Targeting Cytokines in ANCA-Associated Vasculitis

This review explores the use of anti-cytokine targeted therapy for ANCA-associated vasculitis (AAV), a rare group of auto-inflammatory diseases. The review delves into the intricate pathways of inflammation, highlighting the role of cytokines in the development of AAV.

Cytokines: The Shifting Sands of Inflammation

The review examines the specific cytokines involved in AAV, providing insights into the complex interplay of these signaling molecules. The research journey is like navigating a vast and dynamic desert landscape, where the shifting sands of inflammation can create unpredictable pathways.

Managing AAV: A Quest for Effective Therapies

The review explores the potential of anti-cytokine targeted therapy in managing AAV, a rare and potentially life-threatening condition. The goal is to find effective therapies that can tame the storms of inflammation, offering respite in the desert of illness.

Dr.Camel's Conclusion

This review highlights the importance of understanding the intricacies of inflammatory processes in diseases like AAV. It underscores the need for research into targeted therapies that can effectively modulate the immune system and provide relief for patients.
Date :
  1. Date Completed 2020-10-19
  2. Date Revised 2022-11-15
Further Info :

Pubmed ID

32990324

DOI: Digital Object Identifier

PMC8094990

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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