Efficacy and Safety of Up-dosing Antihistamines in Chronic Spontaneous Urticaria: A Systematic Review of the Literature.

Author: , ArmisénM, GonzalezM T, Iriarte SotésP, Meijide CalderónA, Otero RivasM M, Rodriguez FernándezA, Usero-BárcenaT, VeleiroB

Paper Details 
Original Abstract of the Article :
According to current guidelines, oral antihistamines are the first-line treatment for chronic spontaneous urticaria (CSU). Up-dosing antihistamines to 4-fold the licensed dose is recommended if control is not achieved. Such indications are based mainly on expert opinion. Objectives: To critically re...See full text at original site
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引用元:
https://doi.org/10.18176/jiaci.0649

データ提供:米国国立医学図書館(NLM)

Up-dosing Antihistamines: A New Approach to Chronic Spontaneous Urticaria?

Chronic spontaneous urticaria (CSU), a condition characterized by recurrent hives, can be a real itch for patients. This research investigates the efficacy and safety of up-dosing antihistamines, a strategy recommended by current guidelines but lacking extensive evidence. The authors systematically reviewed the literature to analyze the available clinical evidence on this approach. Their findings suggest that up-dosing antihistamines may be a viable option for CSU patients who haven't responded to standard doses, although further research is needed to confirm its effectiveness and safety.

Up-dosing Antihistamines: A Potential Solution for Stubborn Hives?

The authors' findings suggest that up-dosing antihistamines, while not a universal solution, may be an effective approach for a subset of CSU patients. The review highlights the need for more research to establish clear guidelines for using this strategy and to better understand its long-term impact on patients' health. The review also underscores the importance of individualizing treatment plans based on patient responses.

The Quest for Relief: Managing Chronic Spontaneous Urticaria

Dealing with CSU can be a challenging journey for patients, often involving trial and error. This research provides valuable insights into the potential benefits of up-dosing antihistamines, but also highlights the importance of careful monitoring and personalized care. For individuals with CSU, it's essential to consult with their healthcare provider to develop a treatment plan that effectively manages their symptoms.

Dr.Camel's Conclusion

CSU can be as persistent as a desert wind, but this study offers a ray of hope for those seeking relief. The researchers' comprehensive review provides a roadmap for future research, potentially paving the way for better treatment options for CSU patients. Remember, even the smallest change in a treatment strategy can make a big difference for those battling this condition.

Date :
  1. Date Completed 2021-12-13
  2. Date Revised 2021-12-14
Further Info :

Pubmed ID

33030434

DOI: Digital Object Identifier

10.18176/jiaci.0649

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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