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Management of Opioid-Induced and Non-Opioid-Related Constipation in Patients With Cancer: Systematic Review and Meta-Analysis.

Author: GinexPamela K, HansonBrian J, LeFebvreKristine B, LinYufen, MaloneyChristine, MorganRebecca L, MoriartyKerri A, VrabelMark

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

For patients with cancer and opioid-induced constipation, osmotic or stimulant laxatives are moderately beneficial, while methylnaltrexone, naldemedine, and electroacupuncture offer small benefits. For non-opioid-related constipation, naloxegol, prucalopride, lubiprostone, and linaclotide show moderate benefits, while acupuncture has trivial benefit.
Paper Details　
Original Abstract of the Article :
PROBLEM IDENTIFICATION: A systematic review and meta-analysis was conducted to inform the development of national clinical practice guidelines on the management of cancer constipation. LITERATURE SEARCH: PubMed®, Wiley Cochrane Library, and CINAHL® were searched for studies published from May 2009 ...See full text at original site
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引用元：
https://doi.org/10.1188/20.ONF.E211-E224

データ提供：米国国立医学図書館（NLM）

Navigating Constipation in Cancer Patients: A Comprehensive Guide

The field of [Oncology] strives to provide comprehensive care for cancer patients, including managing [constipation], a common and often debilitating side effect of cancer and its treatment. This study provides a [systematic review and meta-analysis] of the literature on the [management of cancer constipation], summarizing the evidence for various treatment approaches. The researchers examined studies published between May 2009 and May 2019, focusing on both [opioid-induced constipation] and [non-opioid-related constipation]. The study provides insights into the [efficacy] of various treatment options, including [lifestyle modifications], [pharmacological interventions], and [complementary therapies].

Unlocking Effective Treatment Strategies for Cancer Constipation

This systematic review and meta-analysis offers a comprehensive guide for managing constipation in cancer patients. The study provides [clinically relevant insights] into the effectiveness of various treatment options, allowing healthcare providers to [make informed decisions] about the most appropriate approaches for their patients. This research is particularly valuable for informing the development of [national clinical practice guidelines] on the management of cancer constipation.

Improving Quality of Life for Cancer Patients

Constipation can significantly impact the quality of life for cancer patients. This study provides a valuable roadmap for healthcare providers to [effectively manage constipation] and [alleviate the discomfort] associated with this common side effect. Like a camel navigating a sandy desert, healthcare providers can use these insights to find the best path to alleviate constipation and improve the well-being of their patients.

Dr.Camel's Conclusion

This comprehensive review offers a valuable resource for healthcare providers seeking to improve the lives of cancer patients by addressing the challenge of constipation. The study provides a roadmap for effective treatment strategies, allowing providers to navigate the complex landscape of cancer care with greater confidence.

Date :
  1. Date Completed 2021-09-17
  2. Date Revised 2021-09-17
Further Info :

Pubmed ID

33063777

DOI: Digital Object Identifier

10.1188/20.ONF.E211-E224

Related Literature

Article Analysis
・Effects of lubiprostone・Effects of naloxegol
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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