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A European Observational Study to Evaluate the Safety and the Effectiveness of Safinamide in Routine Clinical Practice: The SYNAPSES Trial.

Author: , AbbruzzeseGiovanni, BergmansBruno, Gomez-EstebanJuan C, JostWolfgang H, KulisevskyJaime, KägiGeorg, RawJason, StefaniAlessandro, WarneckeTobias

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Observational StudyResearch that observes and collects data on participants' behavior and outcomes in their natural state, without intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

The drug utilization study SYNAPSES was designed to investigate the use of safinamide in routine clinical practice for Parkinson's disease.
Paper Details　
Original Abstract of the Article :
Safinamide modulates both dopaminergic and glutamatergic systems with positive effects on motor and non-motor symptoms of Parkinson's disease (PD). The drug utilization study SYNAPSES was designed to investigate the use of safinamide in routine clinical practice, as recommended by the European Medic...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7990425/

データ提供：米国国立医学図書館（NLM）

Safinamide: A Comprehensive Look in Routine Clinical Practice

This study, like a seasoned traveler exploring a new desert landscape, investigates the use of [safinamide] in the real-world setting of [routine clinical practice]. The authors, with their keen understanding of the challenges faced by patients with [Parkinson's disease (PD)], delve into the effectiveness of [safinamide] in managing both [motor and non-motor symptoms]. This research, like a detailed map, provides a comprehensive overview of [safinamide] utilization.

The [SYNAPSES trial], a [European observational study], acts as a guide, leading researchers through the diverse experiences of patients receiving [safinamide]. The study's design, like a well-planned expedition, ensures a thorough examination of [the safety and effectiveness] of this medication.

Safinamide: A Multifaceted Approach to Parkinson's Disease

This study, like a desert oasis offering multiple sources of sustenance, highlights the multifaceted nature of [safinamide] in treating [Parkinson's disease]. The drug's ability to modulate both [dopaminergic and glutamatergic systems] offers a unique approach to managing the complex symptoms of this debilitating condition.

Navigating the Parkinson's Disease Treatment Landscape

This study, like a desert guide leading travelers to a hidden oasis, reminds us that [continued research and clinical trials] are essential for finding new and effective treatments for [Parkinson's disease]. It's through these journeys of discovery that we can identify promising new options for patients and improve their quality of life.

Dr.Camel's Conclusion

This study offers a comprehensive view of [safinamide] utilization in [routine clinical practice]. The findings highlight its potential in managing both [motor and non-motor symptoms] of [Parkinson's disease]. This research serves as a valuable resource for clinicians and patients alike, providing insight into the real-world use of this medication.

Date :
  1. Date Completed 2021-11-12
  2. Date Revised 2023-11-11
Further Info :

Pubmed ID

33104040

DOI: Digital Object Identifier

PMC7990425

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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