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Tamoxifen related side effects and their impact on breast cancer incidence: A retrospective analysis of the randomised IBIS-I trial.

Author: CuzickJack, DowsettMitch, HaleMichael J, HowellAnthony, SestakIvana

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Endocrine therapy side effects may predict breast cancer recurrence risk. This study assessed the relationship between early reported side effects and breast cancer incidence in women randomized to tamoxifen for cancer prevention.
Paper Details　
Original Abstract of the Article :
Studies in the adjuvant setting have shown that endocrine therapy related side effects predict breast cancer recurrence risk. Here, we assess the relationship between early reported side effects and incidence of breast cancer in women randomised to tamoxifen for cancer prevention in the Internationa...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7649356/

データ提供：米国国立医学図書館（NLM）

Tamoxifen Side Effects and Breast Cancer

This study dives into the exciting world of breast cancer prevention! They're exploring the connection between side effects of tamoxifen, a medication used to prevent breast cancer, and the actual development of the disease. Their approach is like a detective story, using a retrospective analysis of data from the IBIS-I trial, a massive investigation into breast cancer prevention. The authors dug deep into the information collected from women who took tamoxifen and found a link between the side effects they experienced and their risk of developing breast cancer. This research is like a treasure map, guiding us towards a better understanding of how to protect ourselves from breast cancer.

Early Side Effects Signal Potential Risk

It's fascinating how early side effects of tamoxifen can act as a warning sign for breast cancer. The study revealed a connection between the side effects women reported and their likelihood of developing breast cancer. This is like a camel's hump signaling a water source in the desert—a sign that something is happening that might require attention.

Navigating Tamoxifen Side Effects

Knowing about the potential side effects of tamoxifen is crucial for any woman considering this treatment. It's like understanding the desert landscape before embarking on a journey—being aware of the challenges and potential risks allows for better preparation. This research underscores the importance of open communication with your doctor about any side effects, as they can be an important indicator of your individual risk.

Dr.Camel's Conclusion

This research is a reminder that even though medication can be helpful, it's essential to pay attention to our bodies and communicate any changes to our healthcare providers. It's like listening to the whispers of the desert wind—sometimes it's the subtle signs that can lead us to the most crucial information.

Date :
  1. Date Completed 2021-08-11
  2. Date Revised 2021-08-11
Further Info :

Pubmed ID

33160147

DOI: Digital Object Identifier

PMC7649356

Related Literature

Article Analysis
・Side Effects of tamoxifen
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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