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Varicella-zoster-virus vaccination of immunosuppressed children with inflammatory bowel disease or autoimmune hepatitis: A prospective observational study.

Author: AlmanzarGiovanni, CagolLuana, DebatinKlaus-Michael, FrivoltKlara, KoletzkoSibylle, KrahlAndreas, MayerBenjamin, MertensThomas, PosovszkyCarsten, PrelogMartina, SeitelTeresa, SpethFabian, TrenkelStefan

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Observational StudyResearch that observes and collects data on participants' behavior and outcomes in their natural state, without intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Children with inflammatory bowel disease (IBD) and autoimmune hepatitis (AIH) receiving immunosuppressive treatment are at risk for severe varicella zoster virus (VZV) infection. This study evaluated the safety and immunogenicity of varicella zoster virus vaccination in susceptible patients with stable disease and documented immunoreactivity without interrupting their immunosuppression.
Paper Details　
Original Abstract of the Article :
Children with inflammatory bowel disease (IBD) and autoimmune hepatitis (AIH) receiving immunosuppressive treatment are at risk for severe varicella zoster virus (VZV)-induced disease. This study evaluated vaccination of susceptible patients with stable disease and documented immunoreactivity withou...See full text at original site
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引用元：
https://doi.org/10.1016/j.vaccine.2020.10.028

データ提供：米国国立医学図書館（NLM）

Protecting Vulnerable Children: Varicella-Zoster Virus Vaccination

The world of immunizations is constantly evolving, with researchers seeking ways to protect vulnerable populations from preventable diseases. This study focuses on the importance of varicella-zoster virus (VZV) vaccination in children with inflammatory bowel disease (IBD) and autoimmune hepatitis (AIH) who are receiving immunosuppressive treatments. The authors present a prospective observational study evaluating the safety and efficacy of VZV vaccination in these patients, who are at increased risk of severe VZV-induced disease. This study underscores the importance of vaccination in protecting vulnerable individuals.

Vaccination: A Vital Tool

This research emphasizes the critical role of vaccination in safeguarding children with IBD and AIH. The authors demonstrate that vaccination can be safely and effectively administered to these patients without interrupting their current immunosuppressive therapies. Their findings highlight the importance of considering the individual needs of patients and tailoring treatment strategies accordingly.

A Desert of Challenges

The world of healthcare is filled with challenges, especially when it comes to protecting vulnerable populations. This study provides a beacon of hope, showing that vaccination can be a valuable tool in safeguarding children with IBD and AIH. By working together, healthcare professionals can navigate the desert of challenges and ensure that all children have access to the care they need.

Dr. Camel's Conclusion

Like a camel traversing a vast and unforgiving desert, we must be prepared to overcome challenges and find solutions for those in need. This study provides a blueprint for protecting vulnerable children, demonstrating the importance of vaccination in safeguarding their health. The journey toward a healthier future is one we must take together, with compassion, knowledge, and unwavering commitment.

Date :
  1. Date Completed 2021-04-27
  2. Date Revised 2021-04-27
Further Info :

Pubmed ID

33160754

DOI: Digital Object Identifier

10.1016/j.vaccine.2020.10.028

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Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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